Adipokines in non-alcoholic fatty liver disease: are we on the road toward new biomarkers and therapeutic targets?

V Francisco, MJ Sanz, JT Real, P Marques… - Biology, 2022 - mdpi.com
Simple Summary Non-alcoholic fatty liver disease (NAFLD) is an unmet medical need due to
its increasingly high incidence, severe clinical consequences, and the absence of feasible …

[HTML][HTML] The role of novel adipokines and adipose-derived extracellular vesicles (ADEVs): connections and interactions in liver diseases

L Xie, H Wang, J Hu, Z Liu, F Hu - Biochemical Pharmacology, 2024 - Elsevier
Adipose tissues (AT) are an important endocrine organ that secretes various functional
adipokines, peptides, non-coding RNAs, and acts on AT themselves or other distant tissues …

Effects of chemical mixtures on liver function biomarkers in the Korean adult population: thresholds and molecular mechanisms for non-alcoholic fatty liver disease …

HD Nguyen, MS Kim - Environmental Science and Pollution Research, 2022 - Springer
There is a scarcity of research on the effects of a mixture of chemicals on liver function
biomarkers and non-alcoholic fatty liver disease (NAFLD) indices, including FSI, HIS, and …

[HTML][HTML] Identification of heat shock protein family A member 5 (HSPA5) targets involved in nonalcoholic fatty liver disease

A Rehati, B Abuduaini, Z Liang, D Chen, F He - Genes & Immunity, 2023 - nature.com
Heat shock protein family A (Hsp70) member 5 (HSPA5) is an endoplasmic reticulum
chaperone, which regulates cell metabolism, particularly lipid metabolism. While HSPA5's …

Increased RTN3 phenocopies nonalcoholic fatty liver disease by inhibiting the AMPK–IDH2 pathway

H Huang, S Guo, YQ Chen, YX Liu, JY Jin, Y Liang… - MedComm, 2023 - Wiley Online Library
Abstract Reticulon 3 (RTN3), an endoplasmic reticulum protein, is crucial in
neurodegenerative and kidney diseases. However, the role of RTN3 in liver tissues has not …

Heat shock proteins (HSPs) in non-alcoholic fatty liver disease (NAFLD): from molecular mechanisms to therapeutic avenues

Z Nie, C Xiao, Y Wang, R Li, F Zhao - Biomarker Research, 2024 - Springer
Non-alcoholic fatty liver disease (NAFLD), a spectrum of liver conditions characterized by fat
accumulation without excessive alcohol consumption, represents a significant global health …

Cell surface GRP78 regulates TGFβ1-mediated profibrotic responses via TSP1 in diabetic kidney disease

J Trink, U Ahmed, K O'Neil, R Li, B Gao… - Frontiers in …, 2023 - frontiersin.org
Introduction: Diabetic kidney disease (DKD) is the leading cause of kidney failure in North
America, characterized by glomerular accumulation of extracellular matrix (ECM) proteins …

Isoliquiritigenin in combination with visceral adipose tissue and related markers as a predictive tool for nonalcoholic fatty liver disease

P Mogna-Peláez, A Romo-Hualde, JI Riezu-Boj… - Journal of Physiology …, 2023 - Springer
Nonalcoholic fatty liver disease (NAFLD) is the most prevalent form of chronic liver disease
in the world. New non-invasive diagnostic tools are needed to promptly treat this disease …

[HTML][HTML] Adipokines regulate the development and progression of MASLD through organellar oxidative stress

K Zhao, H Zhang, W Ding, X Yu, Y Hou… - Hepatology …, 2025 - journals.lww.com
The prevalence of metabolic dysfunction–associated steatotic liver disease (MASLD), which
is increasingly being recognized as a leading cause of chronic liver pathology globally, is …

Whole-Transcriptome Analysis Sheds Light on the Biological Contexts of Intramuscular Fat Deposition in Ningxiang Pigs

Z Jin, H Gao, Y Fu, R Ren, X Deng, Y Chen, X Hou… - Genes, 2024 - mdpi.com
The quality of pork is significantly impacted by intramuscular fat (IMF). However, the
regulatory mechanism of IMF depositions remains unclear. We performed whole …