Brain tumors represent the second most frequent etiology in patients with focal seizure onset
before 18 years of age and submitted to epilepsy surgery. Hence, this category of brain …

BRAF mutations have been identified as targetable, oncogenic mutations in many cancers.
Given the paucity of treatments for primary brain tumors and the poor prognosis associated …

During the past decade, there have been considerable advances in understanding of the
genetic and morphogenic processes underlying cortical malformations and developmental …

Simple Summary Intramedullary primary spinal cord tumors represent a heterogeneous
group of very rare tumors. In cases of recurrence or high-grade tumors, radiotherapy …

The possible application of BRAF-targeted therapy in brain tumors is growing continuously.
We have analyzed clinical strategies that address BRAF activation in primary brain tumors …

To describe the natural history of spinal gangliogliomas (GG) in order to determine the most
appropriate neuro-oncological management. A Medline search for relevant publications up …

Opinion Statement Molecular heterogeneity has confounded attempts to target individual
pathways in brain tumors. However, gliomas with BRAF mutations have been identified as …

Glioneuronal tumors are very rare CNS neoplasms that demonstrate neuronal
differentiation, composed of mixed glial and neuronal cells. The majority of these lesions are …

Low‐grade neuroepithelial tumors (LNETs) represent an important group of central nervous
system neoplasms, some of which may be associated to epilepsy. The concept of long‐term …

Simple Summary The use of targeted therapies is revolutionizing the prognosis of many
cancers; however, there is still limited knowledge of their side effects. Dyslipidemia is often …