Glycosaminoglycans in tissue engineering: a review

H Sodhi, A Panitch - Biomolecules, 2020 - mdpi.com
Glycosaminoglycans are native components of the extracellular matrix that drive cell
behavior and control the microenvironment surrounding cells, making them promising …

Inflammation in myocardial ischemia/reperfusion injury: underlying mechanisms and therapeutic potential

J Francisco, DP Del Re - Antioxidants, 2023 - mdpi.com
Acute myocardial infarction (MI) occurs when blood flow to the myocardium is restricted,
leading to cardiac damage and massive loss of viable cardiomyocytes. Timely restoration of …

Post-myocardial infarction fibrosis: Pathophysiology, examination, and intervention

X Yin, X Yin, X Pan, J Zhang, X Fan, J Li… - Frontiers in …, 2023 - frontiersin.org
Cardiac fibrosis plays an indispensable role in cardiac tissue homeostasis and repair after
myocardial infarction (MI). The cardiac fibroblast-to-myofibroblast differentiation and …

Biomarkers in cardiorenal syndrome and potential insights into novel therapeutics

EYM Chung, K Trinh, J Li, SH Hahn… - Frontiers in …, 2022 - frontiersin.org
Heart and kidney failure often co-exist and confer high morbidity and mortality. The complex
bi-directional nature of heart and kidney dysfunction is referred to as cardiorenal syndrome …

Impact of reperfusion on temporal immune cell dynamics after myocardial infarction

RYK Zhang, BJ Cochran, SR Thomas… - Journal of the American …, 2023 - Am Heart Assoc
Excessive inflammation and impaired healing of cardiac tissue following a myocardial
infarction (MI) can drive the development of heart failure. Cardiac repair begins immediately …

Therapeutic peptides to treat myocardial ischemia-reperfusion injury

C Fernandez Rico, K Konate, E Josse… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular diseases (CVD) including acute myocardial infarction (AMI) rank first in
worldwide mortality and according to the World Health Organization (WHO), they will stay at …

Progress in cardiac research: from rebooting cardiac regeneration to a complete cell atlas of the heart

SM Davidson, T Padro, S Bollini, G Vilahur… - Cardiovascular …, 2021 - academic.oup.com
We review some of the important discoveries and advances made in basic and translational
cardiac research in 2020. For example, in the field of myocardial infarction (MI), new aspects …

Mitigating neutrophil trafficking and cardiotoxicity with DS–IkL in a microphysiological system of a cytokine storm

VS Shirure, S Yechikov, BS Shergill, T Dehghani… - Lab on a Chip, 2023 - pubs.rsc.org
A feature of severe COVID-19 is the onset of an acute and intense systemic inflammatory
response referred to as the “cytokine storm”. The cytokine storm is characterized by high …

Pioneering a paradigm shift in tissue engineering and regeneration with polysaccharides and proteins-based scaffolds: A comprehensive review

M Angolkar, S Paramshetti, RM Gahtani… - International Journal of …, 2024 - Elsevier
In the realm of modern medicine, tissue engineering and regeneration stands as a beacon
of hope, offering the promise of restoring form and function to damaged or diseased organs …

A Tunable Glycosaminoglycan–Peptide Nanoparticle Platform for the Protection of Therapeutic Peptides

H Sodhi, A Panitch - Pharmaceutics, 2024 - mdpi.com
The popularity of Glycosaminoglycans (GAGs) in drug delivery systems has grown as their
innate ability to sequester and release charged molecules makes them adept in the …