Monomethylarsonic acid (MMA V) and dimethylarsinic acid (DMA V) are active ingredients in
pesticidal products used mainly for weed control. MMA V and DMA V are also metabolites of …

The multi-drug resistance protein 2 (MRP2; ABCC2) is an ATP-binding cassette transporter
playing an important role in detoxification and chemoprotection by transporting a wide range …

In this article, a mechanism of arsenite [As (III)] resistance through methylation and
subsequent volatization is described. Heterologous expression of arsM from …

Arsenic is the most prevalent environmental toxic substance and ranks first on the US
Environmental Protection Agency's Superfund List. Arsenic is a carcinogen and a causative …

Arsenic (As) is a pervasive and ubiquitous environmental toxin that has created worldwide
human health problems. However, there are few studies about how organisms detoxify As …

Arsenic is a naturally occurring metalloid that causes oxidative stress. Exposure of humans,
experimental animals, and cultured cells to arsenic results in a variety of diverse health …

Inorganic arsenic (iAs) at high exposures is a human carcinogen, affecting mainly the
urinary bladder, lung and skin. We present an assessment of the mode of action (MOA) of …

Arsenic is a toxic metalloid abundantly found in nature and used in many industries.
Consumption of contaminated water mainly results in human exposure to arsenic. Toxicity …

Millions of people world-wide are chronically exposed to inorganic forms of the
environmental toxicant arsenic in drinking water. This has led to a public health crisis …

Although inorganic arsenate (iAsV) or arsenite (iAsIII) is clearly a human carcinogen, it has
been difficult to produce tumors in rodents. In the present study, we orally administered iAsV …