Although next-generation sequencing (NGS) technology revolutionized sequencing, offering
a tremendous sequencing capacity with groundbreaking depth and accuracy, it continues to …

Nature achieves differentiation of specific and nonspecific binding in molecular interactions
through precise control of biomolecules in space and time. Artificial systems such as …

Abstract The Integrated Microbial Genomes & Microbiomes system (IMG/M: https://img. jgi.
doe. gov/m/) contains annotated isolate genome and metagenome datasets sequenced at …

Spider silks are among the toughest known materials and thus provide models for
renewable, biodegradable, and sustainable biopolymers. However, the entirety of their …

Enzyme engineering plays a central role in developing efficient biocatalysts for
biotechnology, biomedicine, and life sciences. Apart from classical rational design and …

In recent years, nanopore technology has become increasingly important in the field of life
science and biomedical research. By embedding a nano-scale hole in a thin membrane and …

Background Species-level genetic characterization of complex bacterial communities has
important clinical applications in both diagnosis and treatment. Amplicon sequencing of the …

Metagenomic sequencing for infectious disease diagnostics is an important tool that holds
promise for use in the clinical laboratory. Challenges for implementation so far include high …

Epigenetic pathways are essential in different biological processes and in phenotype-
environment interactions in response to different stressors and they can induce phenotypic …

Assessment of bacterial diversity through sequencing of 16S ribosomal RNA (16S rRNA)
genes has been an approach widely used in environmental microbiology, particularly since …