Obesity, metabolic syndrome, and cancer: pathophysiological and therapeutic associations

N Mili, SA Paschou, DG Goulis, MA Dimopoulos… - Endocrine, 2021 - Springer
Overweight, obesity, and metabolic syndrome (MetS) have become epidemic conditions
affecting 39%, 13%, and 20% of the population respectively. The aim of this article is to …

Weight management and physical activity for breast cancer prevention and control

JA Ligibel, K Basen-Engquist, JW Bea - American Society of Clinical …, 2019 - ascopubs.org
Observational evidence has consistently linked excess adiposity and inactivity to increased
breast cancer risk and to poor outcomes in individuals diagnosed with early-stage …

American Cancer Society guideline for diet and physical activity for cancer prevention

CL Rock, C Thomson, T Gansler… - CA: a cancer journal …, 2020 - Wiley Online Library
Abstract The American Cancer Society (ACS) publishes the Diet and Physical Activity
Guideline to serve as a foundation for its communication, policy, and community strategies …

Logistic LASSO regression for dietary intakes and breast cancer

AJ McEligot, V Poynor, R Sharma, A Panangadan - Nutrients, 2020 - mdpi.com
A multitude of dietary factors from dietary fat to macro and micronutrients intakes have been
associated with breast cancer, yet data are still equivocal. Therefore, utilizing data from the …

Global epidemiology of breast cancer based on risk factors: a systematic review

A Roheel, A Khan, F Anwar, Z Akbar, MF Akhtar… - Frontiers in …, 2023 - frontiersin.org
Background Numerous reviews of the epidemiology and risk factors for breast cancer have
been published previously which heighted different directions of breast cancer. Aim The …

Intentional weight loss and obesity-related cancer risk

J Luo, M Hendryx, JAE Manson… - JNCI cancer …, 2019 - academic.oup.com
Background Epidemiologic studies regarding weight loss and subsequent cancer risk are
sparse. The study aim was to evaluate the association between weight change by …

Sustained weight loss and risk of breast cancer in women 50 years and older: a pooled analysis of prospective data

LR Teras, AV Patel, M Wang, SS Yaun… - JNCI: Journal of the …, 2020 - academic.oup.com
Background Excess body weight is an established cause of postmenopausal breast cancer,
but it is unknown if weight loss reduces risk. Methods Associations between weight change …

SGLT2 inhibition slows tumor growth in mice by reversing hyperinsulinemia

AR Nasiri, MR Rodrigues, Z Li, BP Leitner… - Cancer & Metabolism, 2019 - Springer
Background Obesity confers an increased risk and accelerates the progression of multiple
tumor types in rodents and humans, including both breast and colon cancer. Because …

The many faces of obesity and its influence on breast cancer risk

T Agurs-Collins, SA Ross, BK Dunn - Frontiers in oncology, 2019 - frontiersin.org
Obesity is associated with increased risk of breast and other cancers. However, the
complexity of the underlying mechanisms, together with the interplay of diet and physical …

The role of obesity and bariatric surgery-induced weight loss in breast cancer

MS Bohm, LM Sipe, ME Pye, MJ Davis… - Cancer and Metastasis …, 2022 - Springer
Obesity is a complex metabolic condition considered a worldwide public health crisis, and a
deeper mechanistic understanding of obesity-associated diseases is urgently needed …