Epigenetic pathways play a pivotal role in the development and function of the immune
system. Over the last decade, a growing body of studies has been published out seeking to …

Proteolysis targeting chimeras (PROTACs) are heterobifunctional molecules and allow
selective protein degradation by addressing the natural ubiquitin proteasome system. As this …

The development of new anticancer drugs is necessary in order deal with the disease and
with the drawbacks of currently applied drugs. Epigenetic dysregulations are a central …

Sjögren's syndrome (SjS) and primary biliary cholangitis (PBC) can be classified as a model
of generalized autoimmune epithelitis based on their frequent coexistence in clinical …

Abstract Lysine‐specific demethylase 1 (LSD1/KDM1A) oxidatively removes methyl groups
from histone proteins, and its aberrant activity has been correlated with cancers including …

Cell-active, potent and highly selective chemical reagents with a known mechanism of
action,[1] that is, in brief, the definition of chemical probes that are predominantly used in …

Hundert Jahre nach dem Ersten Weltkrieg und 75 Jahre nach Beginn von Flucht und
Vertreibung nach dem Zweiten Weltkrieg und 30 Jahre nach dem Zerreißen des Eisernen …