Mast cells are tissue-resident cells of the innate immunity, implicated in the pathogenesis of
many autoimmune diseases, including rheumatoid arthritis (RA). They are present in …

Mast cells are potent actors involved in inflammatory reactions in various tissues, including
both in the intimal and the adventitial layers of atherosclerotic arteries. In the arterial intima …

Mast cells are phenotypically and functionally heterogeneous, and their state is possibly
controlled by local microenvironment. Therefore, specific analyses are needed to …

Mast cells (MCs) are critically involved in microbial defense by releasing antimicrobial
peptides (such as cathelicidin LL-37 and defensins) and phagocytosis of microbes. In past …

Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory arthritis, and the complex
interaction and activation of innate and adaptive immune cells are involved in RA …

Background Skin health declines with age and this is partially attributed to
immunosenescence. Mast cells (MCs) are innate immune cells that coordinate tissue …

Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by
inflammation of the synovial membrane, with thickening of the synovial layer, cellular …

Propofol and midazolam are the current standard of care for prolonged sedation in Intensive
Care Units (ICUs). However, the effects and mechanism of these sedatives in brain tissue …

Mast cells are immune cells of the myeloid lineage that are found throughout the body,
including the central nervous system. They perform many functions associated with innate …

Osteoarthritis (OA) is a prevalent joint disease worldwide that significantly impacts the
quality of life of individuals, particularly those in middle-aged and elderly populations. OA …