Acrylamide in bakery products: A review on health risks, legal regulations and strategies to reduce its formation

C Sarion, GG Codină, A Dabija - International Journal of Environmental …, 2021 - mdpi.com
Acrylamide is a contaminant as defined in Council Regulation (EEC) No 315/93 and as
such, it is considered a chemical hazard in the food chain. The toxicity of acrylamide has …

Microbial L-asparaginase for application in acrylamide mitigation from food: Current research status and future perspectives

R Jia, X Wan, X Geng, D Xue, Z Xie, C Chen - Microorganisms, 2021 - mdpi.com
L-asparaginase (EC 3.5. 1.1) hydrolyzes L-asparagine to L-aspartic acid and ammonia,
which has been widely applied in the pharmaceutical and food industries. Microbes have …

[HTML][HTML] Toxicity, formation, contamination, determination and mitigation of acrylamide in thermally processed plant-based foods and herbal medicines: A review

M Fan, X Xu, W Lang, W Wang, X Wang, A Xin… - Ecotoxicology and …, 2023 - Elsevier
Thermal processing is one of the important techniques for most of the plant-based food and
herb medicines before consumption and application in order to meet the specific …

Targeting cancer stem cells and signalling pathways through phytochemicals: A promising approach against colorectal cancer

W Liao, L Zhang, X Chen, J Xiang, Q Zheng, N Chen… - Phytomedicine, 2023 - Elsevier
Abstract Background Cancer stem cells (CSCs) are strongly associated with high
tumourigenicity, chemotherapy or radiotherapy resistance, and metastasis and recurrence …

Nano-gold mediated aptasensor for colorimetric monitoring of acrylamide: Smartphone readout strategy for on-site food control

Z Khoshbin, M Moeenfard, K Abnous, SM Taghdisi - Food Chemistry, 2023 - Elsevier
A simple aptasensor is embedded in the internal surface of a micropipette tip as the
aptasensor substrate for the label-free monitoring of acrylamide. The aptasensor is based on …

Thermostability enhancement and insight of L-asparaginase from Mycobacterium sp. via consensus-guided engineering

H Chi, X Zhu, J Shen, Z Lu, F Lu, Y Lyu… - Applied Microbiology and …, 2023 - Springer
Acrylamide alleviation in food has represented as a critical issue due to its neurotoxic effect
on human health. L-Asparaginase (ASNase, EC 3.5. 1.1) is considered a potential additive …

Enhancing biotechnological applications of l-asparaginase: Immobilization on amino-epoxy-agarose for improved catalytic efficiency and stability

DW de Melo, R Fernandez-Lafuente… - Biocatalysis and …, 2023 - Elsevier
Abstract l-asparaginase has been shown to be effective in reducing acrylamide formation in
food and in treating certain cancers, such as acute lymphoblastic leukemia. This study …

Effective mitigation in the amount of acrylamide through enzymatic approaches

E Abedi, SMB Hashemi, F Ghiasi - Food Research International, 2023 - Elsevier
Acrylamide (AA), as a food-borne toxicant, is created at some stages of thermal processing
in the starchy food through Maillard reaction, fatty food via acrolein route, and proteinous …

[HTML][HTML] Thermostable Chitosan-L-Asparaginase conjugate from Aspergillus fumigatus is a novel structurally stable composite for abolishing acrylamide formation in …

MA Yassin, A Shindia, M Labib, M Soud, ASA El-Sayed - Lwt, 2022 - Elsevier
Abstract l-Asparaginase (Asnase) is one of the most promising approaches for acrylamide
mitigation in foods, however, the enzyme stability and catalytic efficiency are the major …

Exploring current scenario and developments in the field of microbial L-asparaginase production and applications: A review

PG Patel, HZ Panseriya, AK Vala, BP Dave… - Process …, 2022 - Elsevier
L-asparaginase, an amidohydrolase that catalyses break down of L-asparagine into aspartic
acid and ammonia, is one of the most prominent biopharmaceuticals. L-asparaginase (LA) …