The life of eukaryotic cells requires the transport of lipids between membranes, which are
separated by the aqueous environment of the cytosol. Vesicle-mediated traffic along the …

The cell envelope is the first line of defense between a bacterium and the world-at-large.
Often, the initial steps that determine the outcome of chemical warfare, bacteriophage …

Gram-negative bacteria are extraordinarily difficult to kill because their cytoplasmic
membrane is surrounded by an outer membrane that blocks the entry of most antibiotics …

Mutations in the human VPS13 genes are responsible for neurodevelopmental and
neurodegenerative disorders including chorea acanthocytosis (VPS13A) and Parkinson's …

A key event in autophagy is autophagosome formation, whereby the newly synthesized
isolation membrane (IM) expands to form a complete autophagosome using endomembrane …

The outer membrane of Gram-negative bacteria is essential for their survival in harsh
environments and provides intrinsic resistance to many antibiotics. This membrane is …

To replicate inside macrophages and cause tuberculosis, Mycobacterium tuberculosis must
scavenge a variety of nutrients from the host,. The mammalian cell entry (MCE) proteins are …

Cellulose is the most abundant biological compound on Earth and while it is the
predominant building constituent of plants, it is also a key extracellular matrix component in …

In Gram-negative bacteria, lipopolysaccharide is essential for outer membrane formation
and antibiotic resistance. The seven lipopolysaccharide transport (Lpt) proteins A–G move …

Gram-negative bacteria are surrounded by an inner cytoplasmic membrane and by an outer
membrane, which serves as a protective barrier to limit entry of many antibiotics. The …