Depression is a mood disorder that may increase risk for the development of insulin
resistance (IR) and type 2 diabetes (T2D), and vice versa. However, the mechanistic …

Over the past few decades, extensive research has shed light on immune alterations and the
significance of dysfunctional biological barriers in psychiatric disorders. The leaky gut …

BackgroundPrenatal and perinatal complications are established risk factors for psychotic
disorder, but far less is known about these measures and psychotic experiences (PEs). We …

Multiple lines of evidence are known to confirm the pro-inflammatory state of some patients
with schizophrenia and the involvement of inflammatory mechanisms in the pathogenesis of …

Although ETI is well tolerated by most PwCF, some experience debilitating neuropsychiatric
AEs. In some cases, these AEs may be driven by modulation of CFTR and chloride transport …

Background There is some evidence of an association between inflammation in the
pathogenesis of mental disorders. Soluble urokinase plasminogen activator receptor …

Background Converging evidence supports the role of Matrix Metalloproteinases (MMPs) in
psychiatric disorders. Originally identified as regulators of the extracellular matrix (ECM) …

Background Understanding the prenatal origins of children's psychopathology is a
fundamental goal in developmental and clinical science. Recent research suggests that …

Background Identifying circulating biomarkers associated with prospective suicidal ideation
(SI) and depression could help better understand the dynamics of these phenomena and …

Background Chronic low-grade inflammation is observed across mental disorders and is
associated with difficult-to-treat-symptoms of anhedonia and functional brain changes …