Breast cancer diagnosis: Imaging techniques and biochemical markers

SH Jafari, Z Saadatpour… - Journal of cellular …, 2018 - Wiley Online Library
Breast cancer is a complex disease which is found as the second cause of cancer‐
associated death among women. Accumulating of evidence indicated that various factors …

Inflammatory breast cancer biology: the tumour microenvironment is key

B Lim, WA Woodward, X Wang, JM Reuben… - Nature Reviews …, 2018 - nature.com
Inflammatory breast cancer (IBC) is a rare and aggressive disease that accounts for~ 2–4%
of all breast cancers. However, despite its low incidence rate, IBC is responsible for 7–10 …

[HTML][HTML] Breast cancer subtypes predict the preferential site of distant metastases: a SEER based study

Q Wu, J Li, S Zhu, J Wu, C Chen, Q Liu, W Wei… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Results A total of 243,896 patients, including 226,451 cases in control groups were
identified. Bone metastasis was found in 8848 cases, compared with 1,000 brain metastasis …

The multifaceted roles neutrophils play in the tumor microenvironment

RV Sionov, ZG Fridlender, Z Granot - Cancer microenvironment, 2015 - Springer
Neutrophils are myeloid cells that constitute 50–70% of all white blood cells in the human
circulation. Traditionally, neutrophils are viewed as the first line of defense against infections …

The HER-2 receptor and breast cancer: ten years of targeted anti–HER-2 therapy and personalized medicine

JS Ross, EA Slodkowska, WF Symmans… - The …, 2009 - academic.oup.com
Learning Objectives Contrast the current strengths and limitations of the three main slide-
based techniques (IHC, FISH, and CISH) currently in clinical use for testing breast cancer …

Multispecific Platinum (IV) Complex Deters Breast Cancer via Interposing Inflammation and Immunosuppression as an Inhibitor of COX‐2 and PD‐L1

S Jin, N Muhammad, Y Sun, Y Tan, H Yuan… - Angewandte …, 2020 - Wiley Online Library
Breast cancer (BC) is one of the most common malignancies in women and often
accompanied by inflammatory processes. Cyclooxygenase‐2 (COX‐2) plays a vital role in …

TLR agonists: our best frenemy in cancer immunotherapy

S Kaczanowska, AM Joseph… - Journal of leukocyte …, 2013 - academic.oup.com
Review on the ability of different TLR agonists to orchestrate antitumor immune responses,
or promote tumor growth, underscoring the impact of choosing among TLR agonists when …

Mechanisms of the anti-cancer and anti-inflammatory actions of vitamin D

AV Krishnan, D Feldman - Annual review of pharmacology and …, 2011 - annualreviews.org
Calcitriol, the hormonally active form of vitamin D, is being evaluated in clinical trials as an
anti-cancer agent. Calcitriol exerts multiple anti-proliferative, pro-apoptotic, and pro …

The role of cyclooxygenase‐2 in cell proliferation and cell death in human malignancies

C Sobolewski, C Cerella, M Dicato… - … journal of cell …, 2010 - Wiley Online Library
It is well admitted that the link between chronic inflammation and cancer involves cytokines
and mediators of inflammatory pathways, which act during the different steps of …

Derailed endocytosis: an emerging feature of cancer

Y Mosesson, GB Mills, Y Yarden - Nature Reviews Cancer, 2008 - nature.com
Once engaged by soluble or matrix-anchored ligands, cell surface proteins are commonly
sorted to lysosomal degradation through several endocytic pathways. Defective vesicular …