Genetic, environmental, and lifestyle factors primarily determine the lifespan of humans.
From these, nutrition is a key component affecting our health, and several studies …

Neural tissue is one of the main oxygen consumers in the mammalian body, and a
plentitude of metabolic as well as signaling processes within the brain is accompanied by …

Decreased oocyte quality and compromised embryo development are particularly prevalent
in older females, but the aging-related cellular processes and effective ameliorative …

Spermidine (SPD) is a natural polyamine present in all living organisms and is involved in
the maintenance of cellular homeostasis by inducing autophagy in different model …

Normal brain aging is accompanied by intensification of free radical processes and
compromised bioenergetics. Caloric restriction is expected to counteract these changes but …

Caloric restriction (CR) represents a powerful intervention for extending healthspan and
lifespan in several animal models, from yeast to primates. Additionally, in humans, CR has …

Aging-induced neurodegenerative diseases (NDs) are significantly increasing health
problem worldwide. It has been well documented that oxidative stress is one of the potential …

Owing to the global exponential increase in population ageing, there is an urgent unmet
need to develop reliable strategies to slow down and delay the ageing process. Age-related …

Elderly population and age-related diseases are on the rise. On the contrary, aging studies
are technically hard to conduct, because they require elderly animals, the maintenance of …

Ageing is a complex biological process that increases the probability of disease and death,
which affects the organs of all species. The accumulation of oxidative damage in the brain …