The role of serotonin 5-HT2A receptors in memory and cognition
G Zhang, RW Stackman Jr - Frontiers in pharmacology, 2015 - frontiersin.org
Serotonin 5-HT2A receptors (5-HT2ARs) are widely distributed in the central nervous
system, especially in brain region essential for learning and cognition. In addition to …
system, especially in brain region essential for learning and cognition. In addition to …
Monoaminergic neuropathology in Alzheimer's disease
None of the proposed mechanisms of Alzheimer's disease (AD) fully explains the distribution
patterns of the neuropathological changes at the cellular and regional levels, and their …
patterns of the neuropathological changes at the cellular and regional levels, and their …
The serotonergic system and cognitive function
D Švob Štrac, N Pivac, D Mück-Šeler - Translational neuroscience, 2016 - degruyter.com
Symptoms of cognitive dysfunction like memory loss, poor concentration, impaired learning
and executive functions are characteristic features of both schizophrenia and Alzheimer's …
and executive functions are characteristic features of both schizophrenia and Alzheimer's …
The serotonergic system in ageing and Alzheimer's disease
JJ Rodríguez, HN Noristani, A Verkhratsky - Progress in neurobiology, 2012 - Elsevier
Alzheimer's disease (AD) is one of the major neurodegenerative diseases that deteriorates
cognitive functions and primarily affects associated brain regions involved in learning and …
cognitive functions and primarily affects associated brain regions involved in learning and …
Safety, tolerability, pharmacokinetics, and pharmacodynamics of low dose lysergic acid diethylamide (LSD) in healthy older volunteers
N Family, EL Maillet, LTJ Williams, E Krediet… - …, 2020 - Springer
Abstract Research has shown that psychedelics, such as lysergic acid diethylamide (LSD),
have profound anti-inflammatory properties mediated by 5-HT 2A receptor signaling …
have profound anti-inflammatory properties mediated by 5-HT 2A receptor signaling …
State-of-the-art imaging of neuromodulatory subcortical systems in aging and Alzheimer's disease: Challenges and opportunities
N Engels-Domínguez, EA Koops, PC Prokopiou… - Neuroscience & …, 2023 - Elsevier
Primary prevention trials have shifted their focus to the earliest stages of Alzheimer's disease
(AD). Autopsy data indicates that the neuromodulatory subcortical systems'(NSS) nuclei are …
(AD). Autopsy data indicates that the neuromodulatory subcortical systems'(NSS) nuclei are …
Positron emission tomography imaging in dementia
Positron emission tomography (PET) is a well-established imaging modality. Measurement
of regional cerebral glucose metabolism (rCMRglc) using PET and [18F]-2-fluoro-2-deoxy-d …
of regional cerebral glucose metabolism (rCMRglc) using PET and [18F]-2-fluoro-2-deoxy-d …
Serotonin in fear conditioning processes
EP Bauer - Behavioural brain research, 2015 - Elsevier
This review describes the latest developments in our understanding of how the serotonergic
system modulates Pavlovian fear conditioning, fear expression and fear extinction. These …
system modulates Pavlovian fear conditioning, fear expression and fear extinction. These …
Psychedelic‐inspired approaches for treating neurodegenerative disorders
HN Saeger, DE Olson - Journal of neurochemistry, 2022 - Wiley Online Library
Psychedelics are increasingly being recognized for their potential to treat a wide range of
brain disorders including depression, post‐traumatic stress disorder (PTSD), and substance …
brain disorders including depression, post‐traumatic stress disorder (PTSD), and substance …
Principles and management of neuropsychiatric symptoms in Alzheimer's dementia
Neuropsychiatric symptoms of Alzheimer's disease (NPS-AD) are highly prevalent and lead
to poor medical and functional outcomes. In spite of the burdensome nature of NPS-AD, we …
to poor medical and functional outcomes. In spite of the burdensome nature of NPS-AD, we …