Viral hepatitis C: from unravelling the nature of disease to cure and global elimination

V Basyte-Bacevice, L Kupcinskas - Dig Dis, 2024 - karger.com
Background. The discovery of hepatitis C virus (HCV) and direct-acting antiviral (DAA) drugs
are one of the major milestones in the last three decades of medicine. These discoveries …

[HTML][HTML] Epidemiologic and clinical updates on viral infections in Saudi Arabia

NM Alshiban, MS Aleyiydi, MS Nassar… - Saudi Pharmaceutical …, 2024 - Elsevier
In the past two decades, the world has witnessed devastating pandemics affecting the global
healthcare infrastructure and disrupting society and the economy worldwide. Among all …

Genotypes of Hepatitis C virus and efficacy of direct-acting antiviral drugs among chronic hepatitis C patients in a Tertiary Care Hospital

NM Hawsawi, T Saber, HM Salama, WS Fouad… - Tropical Medicine and …, 2023 - mdpi.com
Hepatitis C virus (HCV) chronic infection is a major causative factor for several chronic liver
diseases, including liver cirrhosis, liver cell failure, and hepatocellular carcinoma. The HCV …

Novel 6-Aminoquinazolinone derivatives as potential cross GT1-4 HCV NS5B inhibitors

T Nasr, AM Aboshanab, G Mpekoulis, A Drakopoulos… - Viruses, 2022 - mdpi.com
Chronic hepatitis C virus (HCV) infections are a worldwide medical problem responsible for
diverse types of liver diseases. The NS5B polymerase enzyme has become a very …

Viral Hepatitis C: From Unraveling the Nature of Disease to Cure and Global Elimination

V Basyte-Bacevice, L Kupcinskas - Digestive Diseases, 2024 - karger.com
Background: The discovery of the hepatitis C virus (HCV) and direct-acting antiviral (DAA)
drugs is one of the major milestones in the last 3 decades of medicine. These discoveries …

[HTML][HTML] Real-World Experience, Effectiveness, and Safety of Direct-Acting Antivirals for the Treatment of Hepatitis C in Oman: A Cross-Sectional, Multicenter Study

KM Al-Naamani, H Omar, SA Al Busafi… - Journal of Clinical …, 2024 - mdpi.com
Background: The advent of direct-acting antiviral (DAA) therapy has revolutionized the
treatment landscape of the hepatitis C virus (HCV) infection. This study aimed to provide a …

[HTML][HTML] The Real-World Efficacy and Safety of Direct-Acting Antivirals for Chronic Hepatitis C in Patients Active Malignancies

M Dąbrowska, J Jaroszewicz, M Sitko… - Cancers, 2024 - mdpi.com
Simple Summary In the era of direct-acting antiviral (DAA) agents, chronic hepatitis C virus
(HCV) infection has become a curable disease. Eradication of the virus remains a major …

[HTML][HTML] The Effectiveness and Safety of Direct-Acting Antivirals in the Treatment of Hepatitis C Virus in Saudi Arabia: A Nationwide Study Based on the Saudi Ministry …

TS Al-Ahmari, AF Alotaibi, AI Aljasser, AI Aljasser… - Cureus, 2023 - ncbi.nlm.nih.gov
Methods This was a retrospective cohort study involving recorded HCV cases in the national
hepatitis surveillance database of MOH across all regions of KSA from 2017 to 2021 …

[PDF][PDF] Trends in Hepatocellular Carcinoma among Hepatitis C Patients Achieving Sustained Virological Response Following Direct-Acting Antivirals Treatment

U Maimunah - The Indonesian Journal of Gastroenterology …, 2024 - ina-jghe.com
Hepatitis C continues to be a major worldwide health concern necessitating intervention due
to one of its complications, Hepatocellular Carcinoma (HCC). 1 Data from the World Health …