Cancer stem cells (CSCs), initially identified in leukemia in 1994, constitute a distinct subset
of tumor cells characterized by surface markers such as CD133, CD44, and ALDH. Their …

The insufficient and unspecific target of traditional therapeutic approaches in cancer
treatment often leads to therapy resistance and cancer recurrence. Over the past decades …

Cancer stem cells (CSCs) are the tumor cell subpopulation responsible for resistance to
chemotherapy, tumor recurrence, and metastasis. An efficient therapy must act on low …

Simple Summary Integrins play key roles in mediating cell adhesion and delivering chemical
and mechanical signals to the interior of the cell. Consequently, they actively control cellular …

There is an increasing awareness of the importance of a diet rich in fruits and vegetables for
human health. Cancer stem cells (CSCs) are characterized as a subpopulation of cancer …

Cancer stem cells (CSCs) are a major hindrance to clinical cancer treatment. Owing to their
high tumorigenic and metastatic potential, CSCs are vital in malignant tumor initiation …

Human endogenous retroviruses (HERV), ancient integrations of exogenous viruses, make
up 8% of our genome. Long thought of as mere vestigial genetic elements, evidence is now …

Resistance to anticancer agents and apoptosis results in cancer relapse and is associated
with cancer mortality. Substantial data have provided convincing evidence establishing that …

Malignant melanoma is a tumor characterized by a very high level of heterogeneity,
responsible for its malignant behavior and ability to escape from standard therapies. In this …

Identifying molecular characteristics that are associated with aggressive cancer phenotypes
through gene expression profiling can help predict treatment responses and clinical …