Highlights•Modulation of synaptic strength can occur through changes in short-term
plasticity.•Modulators can shape or induce long-term synaptic plasticity.•Modulators can …

Movement is accomplished by the controlled activation of motor unit populations. Our
understanding of motor unit physiology has been derived from experimental work on the …

The mammalian spinal cord contains a locomotor central pattern generator (CPG) that can
produce alternating rhythmic activity of flexor and extensor motoneurones in the absence of …

The dendrites of motoneurons are not, as once thought, passive conduits for synaptic inputs.
Instead they have voltage‐dependent channels that provide the capacity to generate a very …

Serotonergic neuromodulation contributes to enhanced voluntary muscle activation.
However, it is not known how the likely motoneurone receptor candidate (5‐HT2) influences …

It is now accepted that neurons contain and release multiple transmitter substances.
However, we still have only limited insight into the regulation and functional effects of this co …

Motor fatigue induced by physical activity is an everyday experience characterized by a
decreased capacity to generate motor force. Factors in both muscles and the central nervous …

Immediately after spinal cord injury (SCI), a devastating paralysis results from the loss of
brain stem and cortical innervation of spinal neurons that control movement, including a loss …

Leak potassium currents in the nervous system are often carried through two‐pore‐domain
potassium (K2P) channels. These channels are regulated by a number of different G protein …

Cannabinoids are a structurally diverse group of mostly lipophilic molecules that bind to
cannabinoid receptors. In fact, endogenous cannabinoids (endocannabinoids) are a class of …