Beneficial outcomes of omega-6 and omega-3 polyunsaturated fatty acids on human health: An update for 2021

I Djuricic, PC Calder - Nutrients, 2021 - mdpi.com
Oxidative stress and inflammation have been recognized as important contributors to the risk
of chronic non-communicable diseases. Polyunsaturated fatty acids (PUFAs) may regulate …

Omega− 3 polyunsaturated fatty acids (PUFAs): Emerging plant and microbial sources, oxidative stability, bioavailability, and health benefits—A review

RK Saini, P Prasad, RV Sreedhar, K Akhilender Naidu… - Antioxidants, 2021 - mdpi.com
The omega− 3 (n− 3) polyunsaturated fatty acids (PUFAs) eicosapentaenoic acid (EPA) and
docosahexaenoic (DHA) acid are well known to protect against numerous metabolic …

Effect of high-dose omega-3 fatty acids vs corn oil on major adverse cardiovascular events in patients at high cardiovascular risk: the STRENGTH randomized clinical …

SJ Nicholls, AM Lincoff, M Garcia, D Bash… - Jama, 2020 - jamanetwork.com
Importance It remains uncertain whether the omega-3 fatty acids eicosapentaenoic acid
(EPA) and docosahexaenoic acid (DHA) reduce cardiovascular risk. Objective To determine …

Effect of vitamin D supplementation, omega-3 fatty acid supplementation, or a strength-training exercise program on clinical outcomes in older adults: the DO-HEALTH …

HA Bischoff-Ferrari, B Vellas, R Rizzoli, RW Kressig… - Jama, 2020 - jamanetwork.com
Importance The benefits of vitamin D, omega-3 fatty acids, and exercise in disease
prevention remain unclear. Objective To test whether vitamin D, omega-3s, and a strength …

[HTML][HTML] Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies

WS Harris, NL Tintle, F Imamura, F Qian… - Nature …, 2021 - nature.com
The health effects of omega-3 fatty acids have been controversial. Here we report the results
of a de novo pooled analysis conducted with data from 17 prospective cohort studies …

Omega-3 and omega-6 polyunsaturated fatty acids: Dietary sources, metabolism, and significance—A review

RK Saini, YS Keum - Life sciences, 2018 - Elsevier
Abstract Linoleic acid (LA)(n− 6) and α-linolenic acid (ALA)(n− 3) are essential fatty acids
(EFAs) as they cannot be synthesized by humans or other higher animals. In the human …

Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators

CN Serhan, BD Levy - The Journal of clinical investigation, 2018 - Am Soc Clin Investig
Countless times each day, the acute inflammatory response protects us from invading
microbes, injuries, and insults from within, as in surgery-induced tissue injury. These …

Food in the Anthropocene: the EAT–Lancet Commission on healthy diets from sustainable food systems

W Willett, J Rockström, B Loken, M Springmann… - The lancet, 2019 - thelancet.com
Executive summary Food systems have the potential to nurture human health and support
environmental sustainability; however, they are currently threatening both. Providing a …

Emerging mechanisms of cardiovascular protection for the omega-3 fatty acid eicosapentaenoic acid

RP Mason, P Libby, DL Bhatt - Arteriosclerosis, thrombosis, and …, 2020 - Am Heart Assoc
Patients with well-controlled LDL (low-density lipoprotein) levels still have residual
cardiovascular risk associated with elevated triglycerides. Epidemiological studies have …

Marine omega-3 (N-3) fatty acids for cardiovascular health: an update for 2020

JK Innes, PC Calder - International journal of molecular sciences, 2020 - mdpi.com
The omega-3 (n-3) fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid
(DHA), are found in seafood (especially fatty fish), supplements and concentrated …