The multicellular complexity of peripheral nerve regeneration

AL Cattin, AC Lloyd - Current opinion in neurobiology, 2016 - Elsevier
Highlights•Regeneration of the PNS is a complex, highly coordinated, multicellular process.•
Macrophages have multiple roles to condition the environment for axonal …

Multiscale imaging of plant development by light-sheet fluorescence microscopy

M Ovečka, D von Wangenheim, P Tomančák… - Nature Plants, 2018 - nature.com
Light-sheet fluorescence microscopy (LSFM) methods collectively represent the major
breakthrough in developmental bio-imaging of living multicellular organisms. They are …

The role of neuroinflammation in the transition of acute to chronic pain and the opioid-induced hyperalgesia and tolerance

M Echeverria-Villalobos, V Tortorici, BE Brito… - Frontiers in …, 2023 - frontiersin.org
Current evidence suggests that activation of glial and immune cells leads to increased
production of proinflammatory mediators, creating a neuroinflammatory state …

Transposons as tools for functional genomics in vertebrate models

K Kawakami, DA Largaespada, Z Ivics - Trends in Genetics, 2017 - cell.com
Genetic tools and mutagenesis strategies based on transposable elements are currently
under development with a vision to link primary DNA sequence information to gene …

Satellite glial cells in pain research: a targeted viewpoint of potential and future directions

P Gazerani - Frontiers in Pain Research, 2021 - frontiersin.org
Chronic pain is known to be caused by sensitization within the pain circuits. An imbalance
occurs between excitatory and inhibitory transmission that enables this sensitization to form …

Learning to swim, again: axon regeneration in fish

JP Rasmussen, A Sagasti - Experimental neurology, 2017 - Elsevier
Damage to the central nervous system (CNS) of fish can often be repaired to restore
function, but in mammals recovery from CNS injuries usually fails due to a lack of axon …

Phagocytosis by peripheral glia: Importance for nervous system functions and implications in injury and disease

L Nazareth, J St John, M Murtaza… - Frontiers in Cell and …, 2021 - frontiersin.org
The central nervous system (CNS) has very limited capacity to regenerate after traumatic
injury or disease. In contrast, the peripheral nervous system (PNS) has far greater capacity …

In Vitro, In Vivo and Ex Vivo Models for Peripheral Nerve Injury and Regeneration

A Li, C Pereira, EE Hill, O Vukcevich… - Current …, 2022 - benthamdirect.com
Peripheral Nerve Injuries (PNI) frequently occur secondary to traumatic injuries. Recovery
from these injuries can be expectedly poor, especially in proximal injuries. In order to study …

Gal4 driver transgenic zebrafish: powerful tools to study developmental biology, organogenesis, and neuroscience

K Kawakami, K Asakawa, M Hibi, M Itoh, A Muto… - Advances in …, 2016 - Elsevier
Targeted expression by the Gal4-UAS system is a powerful genetic method to analyze the
functions of genes and cells in vivo. Although the Gal4-UAS system has been extensively …

Schwann cell development: From neural crest to myelin sheath

AN Muppirala, LE Limbach, EF Bradford… - Wiley …, 2021 - Wiley Online Library
Vertebrate nervous system function requires glial cells, including myelinating glia that
insulate axons and provide trophic support that allows for efficient signal propagation by …