Bipolar disorders (BDs) are recurrent and sometimes chronic disorders of mood that affect
around 2% of the world's population and encompass a spectrum between severe elevated …

Bipolar affective disorder is a common neuropsychiatric disorder. Although its
neurobiological underpinnings are incompletely understood, the dopamine hypothesis has …

The Canadian Network for Mood and Anxiety Treatments (CANMAT) previously published
treatment guidelines for bipolar disorder in 2005, along with international commentaries and …

We review recent developments in the acute and long-term treatment of bipolar disorder and
identify promising future routes to therapeutic innovation. Overall, advances in drug …

Bipolar disorder (BD) is a mood disorder with subtypes characterized by episodes of mania,
hypomania, and/or depression. BD is associated with substantial economic burden, and the …

The genetic bases of neuropsychiatric disorders are beginning to yield to scientific inquiry.
Genome-wide studies of copy number variation (CNV) have given rise to a new …

Context Although significant associations of childhood adversities (CAs) with adult mental
disorders have been widely documented, associations of CAs with onset and persistence of …

Objective: We reviewed important clinical aspects of bipolar depression, a progressive
psychiatric condition that is commonly treated in primary care. Bipolar depression is …

Background: Bipolar disorder has generally been regarded as having a better functional
outcome than schizophrenia. However, studies have suggested low functioning in bipolar …

Objective: Schizophrenia and bipolar disorder are associated with multidimensional
disability. This study examined differential predictors of functional deficits in the two …