Clinical course and characteristics of generalized pustular psoriasis

SE Choon, AA Navarini, A Pinter - American Journal of Clinical …, 2022 - Springer
Generalized pustular psoriasis (GPP) is a rare, potentially life-threatening disease
characterized by episodes of widespread sterile macroscopic pustules, with or without …

An update on generalized pustular psoriasis

MJ Gooderham, AS Van Voorhees… - Expert review of clinical …, 2019 - Taylor & Francis
Introduction: Generalized pustular psoriasis (GPP) is a rare, severe relapsing/remitting,
multisystem disease that can be difficult to treat. Recent clinical, histological, and genetic …

[HTML][HTML] Trial of spesolimab for generalized pustular psoriasis

H Bachelez, SE Choon, S Marrakchi… - … England Journal of …, 2021 - Mass Medical Soc
Background Generalized pustular psoriasis (GPP) is a rare, life-threatening, inflammatory
skin disease characterized by widespread eruption of sterile pustules. Interleukin-36 …

Pathophysiology of generalized pustular psoriasis

S Marrakchi, L Puig - American Journal of Clinical Dermatology, 2022 - Springer
Generalized pustular psoriasis (GPP) is a rare, severe form of pustular psoriasis
characterized by widespread, recurrent episodes of neutrophil-rich pustule formation in the …

Prevalence, comorbidities and mortality of generalized pustular psoriasis: a literature review

JC Prinz, SE Choon, CEM Griffiths… - Journal of the …, 2023 - Wiley Online Library
Generalized pustular psoriasis (GPP) is a rare auto‐inflammatory skin disease characterised
by acute episodes of sterile pustule formation. Diagnosis and treatment of the disease have …

Generalized pustular psoriasis: a review and update on treatment

KM Hoegler, AM John, MZ Handler… - Journal of the …, 2018 - Wiley Online Library
Generalized pustular psoriasis (GPP) is a subtype of pustular psoriasis characterized by
painful and occasionally disfiguring cutaneous manifestations with sepsis‐like systemic …

Generalized pustular psoriasis is a disease distinct from psoriasis vulgaris: evidence and expert opinion

H Bachelez, J Barker, AD Burden… - Expert Review of …, 2022 - Taylor & Francis
Introduction Generalized pustular psoriasis (GPP) is a rare, severe, clinically heterogeneous
disease characterized by flares of widespread, noninfectious, macroscopically visible …

Treatment options and goals for patients with generalized pustular psoriasis

J Krueger, L Puig, D Thaçi - American Journal of Clinical Dermatology, 2022 - Springer
Generalized pustular psoriasis (GPP) is a rare, severe neutrophilic skin disorder
characterized by sudden widespread eruption of superficial sterile pustules with or without …

[HTML][HTML] Role of IL-36 cytokines in psoriasis and other inflammatory skin conditions

KL Sachen, CNA Greving, JE Towne - Cytokine, 2022 - Elsevier
The IL-36 family of cytokines includes three pro-inflammatory agonists (IL-36α, IL-36β, and
IL-36γ) and a receptor antagonist (IL-36Ra), which bind and signal through a heterodimeric …

International consensus definition and diagnostic criteria for generalized pustular psoriasis from the International Psoriasis Council

SE Choon, P Van De Kerkhof, JE Gudjonsson… - JAMA …, 2024 - jamanetwork.com
Importance Generalized pustular psoriasis (GPP) lacks internationally accepted definitions
and diagnostic criteria, impeding timely diagnosis and treatment and hindering cross …