TGF-β signaling networks in the tumor microenvironment

MKK Chan, JYF Chung, PCT Tang, ASW Chan, JYY Ho… - Cancer letters, 2022 - Elsevier
Transforming growth factor-β (TGF-β) signaling shows important roles in both physiology
and pathology, especially in the progression of inflammatory diseases including cancer …

Crosstalk between CAFs and tumour cells in head and neck cancer

X Li, C González-Maroto, M Tavassoli - Cell Death Discovery, 2024 - nature.com
Head and neck squamous cell carcinomas (HNSCCs) are amongst the most aggressive,
complex, and heterogeneous malignancies. The standard of care treatments for HNC …

[HTML][HTML] Transforming growth factor-β signaling: from tumor microenvironment to anticancer therapy

MKK Chan, ELY Chan, ZZ Ji, ASW Chan… - … of Targeted Anti …, 2023 - ncbi.nlm.nih.gov
Transforming growth factor-β (TGF-β) signaling is an important pathway for promoting the
pathogenesis of inflammatory diseases, including cancer. The roles of TGF-β signaling are …

Targeting anticancer immunity in oral cancer: Drugs, products, and nanoparticles

L Qin, J Wu - Environmental Research, 2023 - Elsevier
Oral cavity carcinomas are the most frequent malignancies among head and neck
malignancies. Oral tumors include not only oral cancer cells with different potency and …

Biomolecules Involved in Both Metastasis and Placenta Accreta Spectrum—Does the Common Pathophysiological Pathway Exist?

AK Rekowska, K Obuchowska, M Bartosik… - Cancers, 2023 - mdpi.com
Simple Summary Both invasive placentation and cancer metastasis involve the intricate
migration and invasion of cells into the surrounding tissues, while also creating new blood …

Exploring the frontiers: tumor immune microenvironment and immunotherapy in head and neck squamous cell carcinoma

S Liu, R Wang, J Fang - Discover Oncology, 2024 - Springer
The global prevalence of head and neck malignancies positions them as the sixth most
common form of cancer, with the head and neck squamous cell carcinoma (HNSCC) …

[HTML][HTML] Extensive excisional surgery; the last hope for a patient with human papillomavirus-associated severe head and neck squamous cell carcinoma: a case report

N Parizad, N Faraji, R Goli, H Salmanzadeh… - International Journal of …, 2022 - Elsevier
Introduction and importance Cutaneous squamous cell carcinoma (CSCC) is one of the
most common malignant tumors of skin cancer. Most of these cancers occur on the head and …

Targeting TGF beta receptor 1 in head and neck squamous cell carcinoma

BJ Jank, J Schnoell, K Kladnik, C Sparr, M Haas… - Oral …, 2024 - Wiley Online Library
Objectives The transforming growth factor‐Beta (TGF‐ß) pathway may be involved in the
radioresistance of head and neck squamous cell carcinoma (HNSCC). This study analyzed …

[HTML][HTML] Advancements in TGF-β Targeting Therapies for Head and Neck Squamous Cell Carcinoma

WR Britton, I Cioffi, C Stonebraker, M Spence, O Okolo… - Cancers, 2024 - mdpi.com
Simple Summary TGF-β is an important cytokine shown to drive oncogenesis in head and
neck squamous cell carcinoma (HNSCC) through its diverse influences on the tumor …

Revisiting laminin and extracellular matrix remodeling in metastatic squamous cell carcinoma: What have we learned after more than four decades of research?

JD Aleman, CD Young, SD Karam… - Molecular …, 2023 - Wiley Online Library
Patients with squamous cell carcinoma (SCC) have significantly lower survival upon the
development of distant metastases. The extracellular matrix (ECM) is a consistent yet …