Johnson1 proposed that obesity, insulin resistance (IR), and laminitis were components of a
clinical syndrome recognized in horses and ponies. The study of EMS is therefore in its …

Abnormalities of insulin metabolism include hyperinsulinaemia and insulin resistance, and
these problems are collectively referred to as insulin dysregulation in this review. Insulin …

Reasons for performing study: Hyperinsulinaemia is known to induce laminitis
experimentally in healthy ponies with no history of the condition. Horses are more insulin …

Compared with some other species, insulin dysregulation in equids is poorly understood.
However, hyperinsulinemia causes laminitis, a significant and often lethal disease affecting …

Veterinarians have long recognized that obese horses and ponies are prone to laminitis, but
the concept of an equine metabolic syndrome (EMS) was first proposed by Johnson 1 in …

Background Certain individuals appear to be predisposed to recurrent pasture‐associated
laminitis. Previous studies have predominantly investigated risk factors only after disease …

Straightforward testing procedures are needed to facilitate the diagnosis of insulin
dysregulation in horses because hyperinsulinemia and insulin resistance are associated …

Endocrinopathic laminitis is frequently associated with hyperinsulinaemia but the role of
glucose in the pathogenesis of the disease has not been fully investigated. This study aimed …

Equine metabolic syndrome (EMS) refers to a cluster of clinical abnormalities including
insulin resistance, generalized obesity, and/or increased adiposity in specific locations …

It has long been recognized that obesity and insulin resistance (IR) are associated with
increased risk for laminitis in horses and ponies. Furthermore, in a recent informal survey of …