Cross-species RNA-seq for deciphering host–microbe interactions

AJ Westermann, J Vogel - Nature Reviews Genetics, 2021 - nature.com
The human body is constantly exposed to microorganisms, which entails manifold
interactions between human cells and diverse commensal or pathogenic bacteria. The …

[HTML][HTML] Maternal immune activation as an epidemiological risk factor for neurodevelopmental disorders: Considerations of timing, severity, individual differences, and …

MB Hall, DE Willis, EL Rodriguez… - Frontiers in …, 2023 - frontiersin.org
Epidemiological evidence suggests that one's risk of being diagnosed with a
neurodevelopmental disorder (NDD)—such as autism, ADHD, or schizophrenia—increases …

SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice

KH Dinnon III, SR Leist, K Okuda, H Dang… - Science translational …, 2022 - science.org
A subset of individuals who recover from coronavirus disease 2019 (COVID-19) develop
post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Nano-fats for bugs: The benefits of lipid nanoparticles for antimicrobial therapy

CR Thorn, N Thomas, BJ Boyd… - Drug Delivery and …, 2021 - Springer
Bacterial infections are an imminent global healthcare threat evolving from rapidly
advancing bacterial defence mechanisms that antibiotics fail to overcome. Antibiotics have …

[HTML][HTML] Emerging Tick-Borne Dabie bandavirus: Virology, Epidemiology, and Prevention

EH Kim, SJ Park - Microorganisms, 2023 - mdpi.com
Severe Fever with Thrombocytopenia Syndrome (SFTS), caused by Dabie bandavirus
(SFTSV), is an emerging infectious disease first identified in China. Since its discovery …

[HTML][HTML] An immunoresponsive three-dimensional urine-tolerant human urothelial model to study urinary tract infection

NV Jafari, JL Rohn - Frontiers in cellular and infection microbiology, 2023 - frontiersin.org
Introduction Murine models of urinary tract infection (UTI) have improved our understanding
of host-pathogen interactions. However, given differences between rodent and human …

[HTML][HTML] 3D human organoids: the next “viral” model for the molecular basis of infectious diseases

SPS Chia, SLY Kong, JKS Pang, BS Soh - Biomedicines, 2022 - mdpi.com
The COVID-19 pandemic has driven the scientific community to adopt an efficient and
reliable model that could keep up with the infectious disease arms race. Coinciding with the …

[HTML][HTML] Endothelial inflammation and dysfunction in COVID-19

Y Sbirkov, V Dzharov, K Todorova, S Hayrabedyan… - Vasa, 2022 - econtent.hogrefe.com
The biggest challenge in the COVID-19 pandemic besides the spread of the SARS-CoV-2
virus is to reduce mortality rates. As the number of cases continues to rise and new variants …

[HTML][HTML] Mouse models of Japanese encephalitis virus infection: A systematic review and meta-analysis using a meta-regression approach

T Bharucha, B Cleary, A Farmiloe… - PLOS Neglected …, 2022 - journals.plos.org
Background Japanese encephalitis (JE) virus (JEV) remains a leading cause of neurological
infection across Asia. The high lethality of disease and absence of effective therapies mean …

[HTML][HTML] Predictive markers of immunogenicity and efficacy for human vaccines

M Van Tilbeurgh, K Lemdani, AS Beignon, C Chapon… - Vaccines, 2021 - mdpi.com
Vaccines represent one of the major advances of modern medicine. Despite the many
successes of vaccination, continuous efforts to design new vaccines are needed to fight “old” …