Fluorescent cyclic peptides for cell imaging

L Mendive‐Tapia, J Wang, M Vendrell - Peptide Science, 2021 - Wiley Online Library
Fluorescent cyclic peptides are excellent chemical scaffolds to build optical agents for
molecular imaging. In addition to their favorable physicochemical properties, they can be …

Imidazoles and Oxazoles from Lapachones and Phenanthrene‐9, 10‐dione: A Journey through their Synthesis, Biological Studies, and Optical Applications

GG Dias, ERS Paz, MP Nunes… - The Chemical …, 2021 - Wiley Online Library
Diverse structural frameworks are found in natural compounds and are well known for their
chemical and biological properties; such compounds include the imidazoles and oxazoles …

Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease Mpro and Papain-like Protease PLpro of SARS-CoV-2

LH Santos, T Kronenberger, RG Almeida… - Journal of Chemical …, 2022 - ACS Publications
The worldwide COVID-19 pandemic caused by the coronavirus SARS-CoV-2 urgently
demands novel direct antiviral treatments. The main protease (Mpro) and papain-like …

An Activatable Near‐Infrared Molecular Chemiluminescence Probe for Visualization of NQO1 Activity In Vivo

J Liu, Z Chen, H Huo, L Chen, Y Wu… - Chinese Journal of …, 2022 - Wiley Online Library
Comprehensive Summary Chemiluminescence (CL) is a promising tool for diagnostics and
sensing due to its inherent excitation light‐free. However, most CL probes emit exclusively …

It takes two to tango: synthesis of cytotoxic quinones containing two redox active centers with potential antitumor activity

DJB Lima, RG Almeida, GAM Jardim… - RSC Medicinal …, 2021 - pubs.rsc.org
We report the synthesis of 47 new quinone-based derivatives via click chemistry and their
subsequent evaluation against cancer cell lines and the control L929 murine fibroblast cell …

[HTML][HTML] 2, 1, 3-Benzothiadiazoles Are Versatile Fluorophore Building Blocks for the Design of Analyte-Sensing Optical Devices

GG Dias, FT Souto, VG Machado - Chemosensors, 2024 - mdpi.com
BTD s (2, 1, 3-benzothiadiazoles) are fluorescent heterocycles widely used in different
applications, including biomarkers, sensing optical devices, OLEDs, organic transistors, and …

In Vitro and In Vivo Biocompatibility of Natural and Synthetic Pseudomonas aeruginosa Pyomelanin for Potential Biomedical Applications

MM Urbaniak, M Gazińska, K Rudnicka… - International Journal of …, 2023 - mdpi.com
Bacteria are the source of many bioactive compounds, including polymers with various
physiological functions and the potential for medical applications. Pyomelanin from …

NADPH: Quinone oxidoreductase 1 (NQO1) mediated anti-cancer effects of plumbagin in endocrine resistant MCF7 breast cancer cells

N Pradubyat, N Sakunrangsit, A Mutirangura… - Phytomedicine, 2020 - Elsevier
Background PLB is a natural naphthoquinone compound isolated from the roots of
Plumbago indica plant. Our previous study reported the inhibitory effect of Plumbagin (PLB) …

Recent advances in quinone methide chemistry for protein-proximity capturing

YF Gan, YY Li, XQ Chen, YY Guo, R Wang - Synthesis, 2023 - thieme-connect.com
Here we summarize the most recent findings in the chemical-, photo-, or enzyme-triggered
generation of nitrogen and oxygen anions leading to the formation of quinone methide …

Activatable imaging probes for cancer-linked NAD (P) H: quinone oxidoreductase-1 (NQO1): Advances and future prospects

D Su, X Chen, Y Zhang, X Gao - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
Abstract NAD (P) H: quinone oxidoreductase-1 (NQO1) is attractive as a potential cancer
biomarker because it is abnormally expressed in many solid tumors and is closely related to …