CHARMM-GUI Membrane Builder: Past, Current, and Future Developments and Applications
Molecular dynamics simulations of membranes and membrane proteins serve as
computational microscopes, revealing coordinated events at the membrane interface. As G …
computational microscopes, revealing coordinated events at the membrane interface. As G …
[HTML][HTML] Immunopathogenesis of Nipah virus infection and associated immune responses
Pandemics in the last two centuries have been initiated by causal pathogens that include
Severe Acute Coronavirus 2 (SARS-CoV-2) and Influenza (eg, the H1N1 pandemic of 2009) …
Severe Acute Coronavirus 2 (SARS-CoV-2) and Influenza (eg, the H1N1 pandemic of 2009) …
The Ebola virus VP40 matrix layer undergoes endosomal disassembly essential for membrane fusion
SL Winter, G Golani, F Lolicato, M Vallbracht… - The EMBO …, 2023 - embopress.org
Ebola viruses (EBOVs) assemble into filamentous virions, whose shape and stability are
determined by the matrix viral protein 40 (VP40). Virus entry into host cells occurs via …
determined by the matrix viral protein 40 (VP40). Virus entry into host cells occurs via …
[HTML][HTML] The SARS-CoV-2 nucleoprotein associates with anionic lipid membranes
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a lipid-enveloped virus
that acquires its lipid bilayer from the host cell it infects. SARS-CoV-2 can spread from cell to …
that acquires its lipid bilayer from the host cell it infects. SARS-CoV-2 can spread from cell to …
[HTML][HTML] Henipavirus matrix protein employs a non-classical nuclear localization signal binding mechanism
CM Donnelly, OA Vogel, MR Edwards, PE Taylor… - Viruses, 2023 - mdpi.com
Nipah virus (NiV) and Hendra virus (HeV) are highly pathogenic species from the
Henipavirus genus within the paramyxovirus family and are harbored by Pteropus Flying …
Henipavirus genus within the paramyxovirus family and are harbored by Pteropus Flying …
[HTML][HTML] Protracted molecular dynamics and secondary structure introspection to identify dual-target inhibitors of Nipah virus exerting approved small molecules …
S Yang, S Kar - Scientific Reports, 2024 - nature.com
Nipah virus (NiV), with its significantly higher mortality rate compared to COVID-19, presents
a looming threat as a potential next pandemic, particularly if constant mutations of NiV …
a looming threat as a potential next pandemic, particularly if constant mutations of NiV …
High-throughput virtual screening of Streptomyces spp. metabolites as antiviral inhibitors against the Nipah virus matrix protein
Nipah virus (NiV) remains a significant global concern due to its impact on both the
agricultural industry and human health, resulting in substantial economic and health …
agricultural industry and human health, resulting in substantial economic and health …
[HTML][HTML] The “basics” of HIV-1 assembly
C Sumner, A Ono - Plos Pathogens, 2024 - journals.plos.org
Retrovirus particle assembly is driven by a structural protein, Gag (for a comprehensive
review, see [1]). HIV-1 Gag, synthesized as the 55 kDa precursor polyprotein Pr55Gag …
review, see [1]). HIV-1 Gag, synthesized as the 55 kDa precursor polyprotein Pr55Gag …
[HTML][HTML] In silico screening of herbal phytochemicals to develop a Rasayana for immunity against Nipah virus
Background The first emergence of the Nipah virus (NiV) in 1998 from Malaysia became a
major concern when it came to light and resurfaced on different occasions thereafter. NiV is …
major concern when it came to light and resurfaced on different occasions thereafter. NiV is …
Concentrating all helper protein functions on a single entity allows rescue of recombinant Measles virus by transfection of just two plasmids
A Auste, MD Mühlebach - Journal of General Virology, 2022 - microbiologyresearch.org
The generation of recombinant measles virus (MeV) from manipulated genomes on plasmid
DNA is quite a complex and inefficient process. As a member of the order Mononegavirales …
DNA is quite a complex and inefficient process. As a member of the order Mononegavirales …