The symptoms most commonly reported by patients affected by coronavirus disease (COVID-
19) include cough, fever, and shortness of breath. However, other major events usually …

Acute respiratory distress syndrome (ARDS) is a fatal complication of influenza infection. In
this Review we provide an integrated model for its pathogenesis. ARDS involves damage to …

Pulmonary endothelial cells (ECs) are an essential component of the gas exchange
machinery of the lung alveolus. Despite this, the extent and function of lung EC …

Inflammatory lung diseases like asthma bronchiale, chronic obstructive pulmonary disease
and allergic airway inflammation are widespread public diseases that constitute an …

The lung must maintain a proper barrier between airspaces and fluid filled tissues in order to
maintain lung fluid balance. Central to maintaining lung fluid balance are epithelial cells …

The severe acute respiratory syndrome associated coronavirus-2 (SARS-CoV-2) poses a
threat to human life worldwide. Since early March, 2020, coronavirus disease 2019 (COVID …

Influenza A virus (IAV) infects the respiratory tract in humans and causes significant
morbidity and mortality worldwide each year. Aggressive inflammation, known as a cytokine …

Statins not only reduce levels of LDL-cholesterol, they counteract the inflammatory changes
associated with acute coronary syndrome and improve survival. Similarly, in patients …

Epithelial permeability is a hallmark of mucosal inflammation, but the molecular mechanisms
involved remain poorly understood. A key component of the epithelial barrier is the apical …

Influenza virus (IFV) is a major respiratory pathogen of global importance, and the cause of a
high degree of morbidity and mortality, especially in high-risk populations such as infants …