Background: Tendon and ligament injuries accounted for 30% of all musculoskeletal
consultations with 4 million new incidences worldwide each year and thus imposed a …

Anterior cruciate ligament (ACL) tear is common in sports and accidents, and accounts for
over 50% of all knee injuries. ACL reconstruction (ACLR) is commonly indicated to restore …

Anterior cruciate ligament (ACL) reconstruction is the recommended treatment for ACL tear
in the American Academy of Orthopaedic Surgeons (AAOS) guideline. However, not a small …

Background Anterior cruciate ligament (ACL) repair techniques are new emerging strategies
prevailing, in selected cases, over standard reconstruction of the ACL with excision of its …

Skeletal muscle possesses remarkable adaptability to mechanical loading and regenerative
potential following muscle injury primarily due to satellite cell activity. Although the roles of …

Exercise is widely recognized as beneficial for tendon healing. Recently, it has been
described that muscle-derived molecules secreted in response to static exercise influence …

In organisms from flies to mammals, the initial formation of a functional tendon is completely
dependent on chemical signals from muscles (myokines). However, how myokines affect the …

Tendon injuries and disorders associated with mechanical tendon overuse are common
musculoskeletal problems. Even though tendons play a central role in human movement …

It is known that mechanical loading of muscles increases the strength of healing tendon
tissue, but the mechanism involved remains elusive. We hypothesized that the secretome …

Background: The removal of all adherent muscle tissue from the hamstring graft during
anterior cruciate ligament reconstruction (ACLR) is common practice. However, there is a …