D-Amino acid oxidase (DAAO) is an FAD-containing flavoenzyme that catalyzes with
absolute stereoselectivity the oxidative deamination of all natural D-amino acids, the only …

D-amino acid oxidase (DAO) is a flavoenzyme that metabolizes certain D-amino acids,
notably the endogenous N-methyl D-aspartate receptor (NMDAR) co-agonist, D-serine. As …

Within the last few years, knowledge about vitamins has increased dramatically. This new
edition of a bestseller presents comprehensive summaries that analyze the chemical …

Schizophrenia is a severe mental illness that affects~ 1% of the world's population. It is
clinically characterized by positive, negative, and cognitive symptoms. Currently available …

Abstract Alzheimer's disease (AD), the main cause of dementia worldwide, is characterized
by a complex and multifactorial etiology. In large part, excitatory neurotransmission in the …

Over the past years, accumulating evidence has indicated that d-serine is the endogenous
ligand for the glycine-modulatory binding site on the NR1 subunit of N-methyl-d-aspartate …

Hepatocellular carcinoma (HCC) has a high incidence and mortality worldwide, and its
carcinogenesis and progression are influenced by a complex network of gene interactions …

Over the years, accumulating evidence has indicated that D-serine represents the
endogenous ligand for the glycinemodulatory binding site on the NR1 subunit of N-methyl-D …

Since d-amino acids were identified in mammals, d-serine has been one of the most
extensively studied “unnatural amino acids”. This brain-enriched transmitter-like molecule …

In the brain, the non‐essential amino acid L‐serine is produced through the phosphorylated
pathway (PP) starting from the glycolytic intermediate 3‐phosphoglycerate: among the …