This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …

Atherosclerosis (AS) is the major form of cardiovascular disease and the leading cause of
morbidity and mortality in countries around the world. Atherosclerosis combines the …

Vascular endothelial cells (ECs) are exposed to hemodynamic forces, which modulate EC
functions and vascular biology/pathobiology in health and disease. The flow patterns and …

Atherosclerosis is an inflammatory disease of the wall of large-and medium-sized arteries
that is precipitated by elevated levels of low-density lipoprotein (LDL) cholesterol in the …

Atherosclerosis remains a major cause of morbidity and mortality worldwide, and a thorough
understanding of the underlying pathophysiological mechanisms is crucial for the …

The heterogeneity of plaque formation, the vascular remodelling response to plaque
formation, and the consequent phenotype of plaque instability attest to the extraordinarily …

Cardiovascular disease (CVD) is the leading cause of mortality worldwide, accounting for
16.7 million deaths each year. The underlying cause of the majority of CVD is …

In many ways, atherosclerosis is a chronic inflammatory disorder and this issue is confirmed
by recent investigations of that have focused on inflammation, providing new insight into …

The fundamental importance of chemokines for atherogenesis, progression, and
destabilization of atherosclerotic plaques is now widely appreciated, but the degree of …

Immune responses are dependent on the recruitment of leukocytes to the site of
inflammation. The classical leukocyte recruitment cascade, consisting of capture, rolling …