Brain “fog,” inflammation and obesity: key aspects of neuropsychiatric disorders improved by luteolin

TC Theoharides, JM Stewart, E Hatziagelaki… - Frontiers in …, 2015 - frontiersin.org
Brain “fog” is a constellation of symptoms that include reduced cognition, inability to
concentrate and multitask, as well as loss of short and long term memory. Brain “fog” …

Recent advances in our understanding of mast cell activation–or should it be mast cell mediator disorders?

TC Theoharides, I Tsilioni, H Ren - Expert review of clinical …, 2019 - Taylor & Francis
Introduction: An increasing number of patients present with multiple symptoms affecting
many organs including the brain due to multiple mediators released by mast cells. These …

Brain fog: A narrative review of the most common mysterious cognitive disorder in COVID-19

M Aghajani Mir - Molecular Neurobiology, 2024 - Springer
It has been more than three years since COVID-19 impacted the lives of millions of people,
many of whom suffer from long-term effects known as long-haulers. Notwithstanding …

The novel flavone tetramethoxyluteolin is a potent inhibitor of human mast cells

Z Weng, AB Patel, S Panagiotidou… - Journal of Allergy and …, 2015 - Elsevier
Background Mast cells (MCs) are hematopoietic cells that mature in tissues and are involved
in allergy, immunity, and inflammation by secreting multiple mediators. The natural flavone …

The microbiome and eating disorders

J Seitz, S Trinh, B Herpertz-Dahlmann - Psychiatric Clinics, 2019 - psych.theclinics.com
The human body carries at least as many gut microbial cells as total eukaryotic cells. 1 Out
of approximately 1000 different gut microbial species, each human being hosts his or her …

Effects of mycotoxins on neuropsychiatric symptoms and immune processes

AM Ratnaseelan, I Tsilioni, TC Theoharides - Clinical therapeutics, 2018 - Elsevier
Purpose The effects of air pollutants have been receiving increased attention both clinically
and in the media. One such pollutant is mold, fungal growth in the form of multicellular …

Mast cells, brain inflammation and autism

TC Theoharides, JM Stewart, S Panagiotidou… - European journal of …, 2016 - Elsevier
Increasing evidence indicates that brain inflammation is involved in the pathogenesis of
neuropsychiatric diseases. Mast cells (MCs) are located perivascularly close to neurons and …

Mast cell activation in brain injury, stress, and post-traumatic stress disorder and Alzheimer's disease pathogenesis

D Kempuraj, GP Selvakumar, R Thangavel… - Frontiers in …, 2017 - frontiersin.org
Mast cells are localized throughout the body and mediate allergic, immune, and
inflammatory reactions. They are heterogeneous, tissue-resident, long-lived, and granulated …

Molecular and cellular mechanisms that initiate pain and itch

J Luo, J Feng, S Liu, ET Walters, H Hu - Cellular and molecular life …, 2015 - Springer
Somatosensory neurons mediate our sense of touch. They are critically involved in
transducing pain and itch sensations under physiological and pathological conditions, along …

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and comorbidities: linked by vascular pathomechanisms and vasoactive mediators?

KJ Wirth, M Löhn - Medicina, 2023 - mdpi.com
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is often associated with
various other syndromes or conditions including mast cell activation (MCA), dysmenorrhea …