What can be expected in normal aging, and where does normal aging stop and pathological
neurodegeneration begin? With the slow progression of age-related dementias such as …

Lesion studies link the prefrontal cortex (PFC) to executive functions. However, the evidence
from in vivo investigations in healthy people is mixed, and there are no quantitative …

Research concerned with relations between adult age and cognitive functioning is briefly
reviewed. The coverage is necessarily selective, and is organized in terms of five major …

The structure of the brain is constantly changing from birth throughout the lifetime, meaning
that normal aging, free from dementia, is associated with structural brain changes. This …

Voxel-based-morphometry (VBM) is a whole-brain, unbiased technique for characterizing
regional cerebral volume and tissue concentration differences in structural magnetic …

As we grow older, we may grow wiser, but we can also experience memory loss and
cognitive slowing that can interfere with our daily routines. The cognitive neuroscience of …

Critical requirements for the hypothesis that executive functioning is a potential mediator of
age-related effects on cognitive functioning are that variables assumed to reflect executive …

Cross-sectional magnetic resonance imaging (MRI) studies of cortical thickness and volume
have shown age effects on large areas, but there are substantial discrepancies across …

There are many reports of relations between age and cognitive variables and of relations
between age and variables representing different aspects of brain structure and a few …

This target article considers the relation of fluid cognitive functioning to general intelligence.
A neurobiological model differentiating working memory/executive function cognitive …