The gut microbiome is critical in providing resistance against colonization by exogenous
microorganisms. The mechanisms via which the gut microbiota provide colonization …

One of the most exciting developments in the field of bacterial pathogenesis in recent years
is the discovery that many pathogens utilize complex nanomachines to deliver bacterially …

Shigella spp. are a common cause of diarrheal disease and have remained an important
pathogen responsible for increased rates of morbidity and mortality caused by dysentery …

Flagellar and translocation-associated type III secretion (T3S) systems are present in most
Gram-negative plant-and animal-pathogenic bacteria and are often essential for bacterial …

Shigella spp. are gram-negative pathogenic bacteria that evolved from harmless
enterobacterial relatives and may cause devastating diarrhea upon ingestion. Research …

Our understanding of bacterial pathogenesis is dominated by the cell biology of the host–
pathogen interaction. However, the majority of metabolites that are used in prokaryotic and …

Bacteria have developed remarkable systems that sense neighboring target cells upon
contact and initiate a series of events that enhance their survival and growth at the expense …

Abstract The Type III Secretion System (T3SS) is a multi-mega Dalton apparatus assembled
from more than twenty components and is found in many species of animal and plant …

The type III secretion machinery of Gram‐negative bacteria, also known as the injectisome
or needle complex, is composed of a basal body spanning both bacterial membranes and …

Bacterial pathogens have coevolved with humans in order to efficiently infect, replicate
within, and be transmitted to new hosts to ensure survival and a continual infection cycle. For …