Sulfonamide compounds, also known as sulfa drugs, are a significant class of synthetic
bacteriostatic antimicrobials and were the primary source of therapy against bacterial …

Parasitic diseases are a public health problem, especially in developing countries where
millions of people are affected every year. Current treatments have several drawbacks …

Infections caused by Fasciola species are widely distributed in cattle and sheep causing
significant economic losses, and are emerging as human zoonosis with increasing reports of …

Effective macrofilaricidal drugs are not commercially available, and in an endeavour to find
out new macrofilaricidal agents, in this research work, thiosemicarbazone derivatives have …

A novel library of synthetic piperidine derivatives was used to screen against human
lymphatic filarial parasite Brugia malayi. Piperidine has earlier been reported to have effect …

Purpose Oxidative stress is an essential component of innate response against microbes.
The oxidative impact has a very subtle connection with apoptosis. Our previous work …

Lymphatic filariasis is a global problem as far as morbidity is concerned with the high risk of
re-emergence. Threfore, its elimination is a challenge to the developing countries. The …