[HTML][HTML] Machine learning in drug discovery: a review

S Dara, S Dhamercherla, SS Jadav, CHM Babu… - Artificial intelligence …, 2022 - Springer
This review provides the feasible literature on drug discovery through ML tools and
techniques that are enforced in every phase of drug development to accelerate the research …

Multimodal data fusion for cancer biomarker discovery with deep learning

S Steyaert, M Pizurica, D Nagaraj… - Nature machine …, 2023 - nature.com
Technological advances have made it possible to study a patient from multiple angles with
high-dimensional, high-throughput multiscale biomedical data. In oncology, massive …

oncoPredict: an R package for predicting in vivo or cancer patient drug response and biomarkers from cell line screening data

D Maeser, RF Gruener, RS Huang - Briefings in bioinformatics, 2021 - academic.oup.com
Cell line drug screening datasets can be utilized for a range of different drug discovery
applications from drug biomarker discovery to building translational models of drug …

Artificial intelligence-based multi-omics analysis fuels cancer precision medicine

X He, X Liu, F Zuo, H Shi, J Jing - Seminars in Cancer Biology, 2023 - Elsevier
With biotechnological advancements, innovative omics technologies are constantly
emerging that have enabled researchers to access multi-layer information from the genome …

Applications of machine learning in drug discovery and development

J Vamathevan, D Clark, P Czodrowski… - Nature reviews Drug …, 2019 - nature.com
Drug discovery and development pipelines are long, complex and depend on numerous
factors. Machine learning (ML) approaches provide a set of tools that can improve discovery …

[HTML][HTML] Artificial intelligence and machine learning in precision and genomic medicine

S Quazi - Medical Oncology, 2022 - Springer
The advancement of precision medicine in medical care has led behind the conventional
symptom-driven treatment process by allowing early risk prediction of disease through …

[HTML][HTML] How machine learning will transform biomedicine

J Goecks, V Jalili, LM Heiser, JW Gray - Cell, 2020 - cell.com
This Perspective explores the application of machine learning toward improved diagnosis
and treatment. We outline a vision for how machine learning can transform three broad …

Genomics to select treatment for patients with metastatic breast cancer

F Andre, T Filleron, M Kamal, F Mosele, M Arnedos… - Nature, 2022 - nature.com
Cancer progression is driven in part by genomic alterations. The genomic characterization of
cancers has shown interpatient heterogeneity regarding driver alterations, leading to the …

Gut microbiome, big data and machine learning to promote precision medicine for cancer

G Cammarota, G Ianiro, A Ahern, C Carbone… - Nature reviews …, 2020 - nature.com
The gut microbiome has been implicated in cancer in several ways, as specific microbial
signatures are known to promote cancer development and influence safety, tolerability and …

[HTML][HTML] Next-generation machine learning for biological networks

DM Camacho, KM Collins, RK Powers, JC Costello… - Cell, 2018 - cell.com
Machine learning, a collection of data-analytical techniques aimed at building predictive
models from multi-dimensional datasets, is becoming integral to modern biological research …