Dedifferentiated liposarcoma: systemic therapy options

Z Gahvari, A Parkes - Current treatment options in oncology, 2020 - Springer
Opinion statement Over the last several years, the systemic treatment landscape for
dedifferentiated liposarcoma (DDLPS) has notably expanded. Historically, systemic therapy …

[HTML][HTML] Current unmet needs in locally advanced (unresectable) or metastatic dedifferentiated liposarcoma, the relevance of progression-free survival as clinical …

P Schöffski, RL Jones, M Agulnik, JY Blay, A Chalmers… - ESMO open, 2024 - Elsevier
Background Locally advanced (unresectable) or metastatic dedifferentiated liposarcoma
(DDLPS) is a common presentation of liposarcoma. Despite established diagnostic and …

[HTML][HTML] Deciphering the roles of non-coding RNAs in liposarcoma development: Challenges and opportunities for translational therapeutic advances

ZX Chong, WY Ho, SK Yeap - Non-coding RNA Research, 2024 - Elsevier
Liposarcoma is one of the most prevalent forms of soft tissue sarcoma, and its prognosis is
highly dependent on its molecular subtypes. Non-coding RNAs (ncRNAs) like microRNAs …

[HTML][HTML] Targeted transcriptomic analysis of well-differentiated and dedifferentiated liposarcoma reveals multiple dysregulated pathways including glucose metabolism …

A Patton, N Horn, P Upadhaya, P Sarchet… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
Liposarcoma is the most prevalent sarcoma in adults representing 20% of all sarcomas with
well-differentiated/dedifferentiated among the most common subtypes represented. Despite …

Transmediastinal primary pulmonary liposarcoma: Case report and review of management strategies

T Wilcox, A Kleinertz, BD Seadler, LD Joyce… - Rare …, 2024 - journals.sagepub.com
Soft tissue sarcomas account for less than 1% of new cancer diagnoses, approximately one
in five of which are liposarcomas. These tumors typically arise in the deep tissues of the …

Myogenic dedifferentiation is associated with poor outcomes in retroperitoneal dedifferentiated liposarcomas

GO Dorian Yarih, CS Claudia HS, AC Alethia… - Rare …, 2021 - journals.sagepub.com
Sarcomas are a heterogenous group of malignant tumors with origin or mesenchymal
differentiation, they comprise 1–2% of all solid tumors. Retroperitoneum is the second most …

[PDF][PDF] Current unmet needs in locally advanced (unresectable) or metastatic dedifferentiated liposarcoma, the relevance of progression-free survival as clinical …

M Agulnik, A Chalmers, A ITALIANO… - 2024 - scientiasalut.gencat.cat
Background Locally advanced (unresectable) or metastatic dedifferentiated liposarcoma
(DDLPS) is a common presentation of liposarcoma. Despite established diagnostic and …