Recent advances in continuous-flow organocatalysis for process intensification

C De Risi, O Bortolini, A Brandolese… - Reaction Chemistry & …, 2020 - pubs.rsc.org
Chemistry in continuous-flow continues to attract attention from the community of synthetic
organic chemists due to its now well-recognized benefits including, inter alia, quick reaction …

α, β-Unsaturated acyl ammonium species as reactive intermediates in organocatalysis: an update

J Bitai, MT Westwood, AD Smith - Organic & Biomolecular Chemistry, 2021 - pubs.rsc.org
α, β-Unsaturated acyl ammonium species are versatile intermediates that have been applied
in a variety of transformations including Michael additions, domino reactions and …

Efficient esterification of n-butanol with acetic acid catalyzed by the Brönsted acidic ionic liquids: influence of acidity

J Lunagariya, A Dhar, RL Vekariya - RSC advances, 2017 - pubs.rsc.org
The efficiency in the catalytic performance of halogen free functionalized room-temperature
Brönsted acidic ionic liquids (BAILs), having different acidities (due to the ILs containing …

Organocatalytic transformations in deep eutectic solvents: Green methodologies made greener

N Fanjul-Mosteirín, V del Amo - Tetrahedron, 2021 - Elsevier
Nowadays large quantities of volatile organic compounds (VOCs) are used, although they
present serious disadvantages. Developing alternative reaction media capable of replacing …

A multifunctional triazine-based nanoporous polymer as a versatile organocatalyst for CO 2 utilization and C–C bond formation

R Sharma, A Bansal, CN Ramachandran… - Chemical …, 2019 - pubs.rsc.org
A triazine-based nanoporous multifunctional polymer with a SABET of 304 m2 g− 1 has
shown versatile catalytic activity in the conversion of CO2 to cyclic carbonates at 4 bar with …

Thermochemical and electrochemical CO2 reduction by a cyclophosphazene and triazine based inorganic–organic hybrid nanoporous metal-free catalyst

J Das, R Sharma, S Balhara, P Mohanty - Fuel, 2023 - Elsevier
Abstract Heteroatom enriched (S= 46 wt%, N= 21 wt%) cyclophosphazene and triazine
based hybrid nanoporous material (CTHM-2) is reported as an efficient metal free catalyst …

Expanding the Toolbox of Heterogeneous Asymmetric Organocatalysts: Bifunctional Cyclopropenimine Superbases for Enantioselective Catalysis in Batch and …

C Leonardi, A Brandolese, L Preti… - Advanced Synthesis …, 2021 - Wiley Online Library
A strategy for the immobilization of chiral 2, 3‐bisaminocyclopropenium salt (pre‐catalyst)
onto polystyrene and silica supports is presented together with a suitable procedure for the …

Process Development for the First GMP Synthesis of SGD-9501-TFA, Part 2: Synthesis of the Payload, Linker, and Drug Linker

K Payne, JC Tran, B Gill, W Guy… - … Process Research & …, 2024 - ACS Publications
The discovery of novel auristatin-derived antibody drug conjugates (ADCs) with attenuated
bystander activity is an area of intense research. Recently, drug-linker SGD-9501-TFA …

Recent advances in synthesizing and utilizing nitrogen-containing heterocycles

HJ Ha - Frontiers in Chemistry, 2023 - frontiersin.org
The use of organocatalysts and a pot economy has strengthened recent organic syntheses.
Synthetic methodologies may be applicable in laboratory preparation or in the industrial …

Questions in natural products synthesis research that can (and cannot) be answered using computational chemistry

DJ Tantillo - Chemical Society Reviews, 2018 - pubs.rsc.org
Questions in natural products synthesis research that can (and cannot) be answered using
computational chemistry - Chemical Society Reviews (RSC Publishing) DOI:10.1039/C8CS00298C …