Diabetic retinopathy (DR), the most common microvascular complication of diabetes
mellitus, represents the leading cause of acquired blindness in the working-age population …

The endothelial glycocalyx (EG) is a meshlike network present on the apical surface of the
endothelium. Membrane-bound proteoglycans, the major backbone molecules of the EG …

Background The incidence of diabetic kidney disease (DKD) continues to rapidly increase,
with limited available treatment options. One of the hallmarks of DKD is persistent …

Background Diabetic retinopathy (DR), a neurovascular disease, is a leading cause of visual
loss worldwide and severely affects quality of life. Several studies have shown that …

Introduction The endothelial glycocalyx regulates vascular permeability, inflammation, and
coagulation, and acts as a mechanosensor. The loss of glycocalyx can cause endothelial …

Proliferative diabetic retinopathy (PDR), a major complication of diabetes mellitus, results
from an inflammation-sustained interplay among endothelial cells, neurons, and glia. Even …

Diabetic retinopathy (DR) is a common microvascular complication of diabetes and a
leading cause of vision loss worldwide. Although several mechanisms have been implicated …

Syndecan (SDC) is a member of the heparan sulfate proteoglycan (HSPG) family. It appears
to play a role in the aetiology of diabetic complications, with decreased levels of SDCs being …

Background The endothelial glycocalyx (EG) is essential for maintaining microvascular
homeostasis. However, the relationship between the EG and coronary microcirculation …

Purpose. Previous studies suggest that the endothelial glycocalyx adds to vascular
resistance, inhibits thrombosis, and is critical for regulating homogeneous blood flow and …