Simple Summary Metastasis is one of the biggest challenges in treating breast cancer.
Breast tumors grow in different areas such as the brain, lungs and bone and have distinct …

Autotaxin (ATX) is an extracellular secretory enzyme (lysophospholipase D) that catalyzes
the hydrolysis of lysophosphatidyl choline to lysophosphatidic acid (LPA). The ATX–LPA …

Autotaxin (ATX) or Ectonucleotide Pyrophosphatase/Phosphodiesterase 2 (ENPP2) is a
secreted enzyme with lysophospholipase D activity, with its primary function being the …

The COVID-19 pandemic caused by the SARS-CoV-2 virus has greatly affected global
health. Emerging evidence suggests a complex interplay between Alzheimer's disease (AD) …

Myocardial ischemia-reperfusion injury (I/R) causes damage to cardiomyocytes through
oxidative stress and apoptosis. We investigated the cardioprotective effects of MnTnBuOE-2 …

Cardiomyocyte survival is a critical contributing process of host adaptive responses to
cardiovascular diseases (CVD). Cells of the cardiovascular endothelium have recently been …

Neointimal hyperplasia is characterized by a loss of the contractile phenotype of vascular
smooth muscle cells (VSMCs). Our group has recently shown that VSMC proliferation and …

Simple Summary Crystalline silica particles (CSi) are carcinogenic; however, their
genotoxicity is not well characterized. Indirect evidence suggests that retained particles in …

Les calcifications cardiovasculaires, également appelées calcifications ectopiques, sont un
phénomène pathologique très fréquent. Leur développement est étroitement associé au …

This comprehensive study investigates the pivotal roles of Autotaxin (ATX), lysophosphatidic
acid (LPA), and lipid phosphate phosphatase 3 (LPP3) in the context of vascular …