Over the last decade, stem cell-based regenerative medicine has progressed to clinical
testing and therapeutic applications. The applications range from infusions of autologous …

Cartilage tissue engineering is becoming increasingly popular for repairing cartilage
defects. However, lack of nerves and blood vessels, as well as low cell density cause …

Distinctive characteristics of articular cartilage such as avascularity and low chondrocyte
conversion rate present numerous challenges for orthopedists. Tissue engineering is a …

Background The approaches currently used in osteoarthritis (OA) are mainly short-term
solutions with unsatisfactory outcomes. Cell-based therapies are still controversial (in terms …

Human articular cartilage has a poor ability to self‐repair, meaning small injuries often lead
to osteoarthritis, a painful and debilitating condition which is a major contributor to the global …

The remarkable lubrication properties of normal articular cartilage play an essential role in
daily life, providing almost frictionless movements of joints. Alterations of cartilage surface or …

Osteochondral injuries can lead to osteoarthritis (OA). OA is characterized by the
progressive degradation of the cartilage tissue together with bone tissue turnover …

Cartilage damage affects millions of people worldwide. Tissue engineering strategies hold
the promise to provide off‐the‐shelf cartilage analogs for tissue transplantation in cartilage …

Osteoarthritis (OA), the most common chronic joint disease, is a degenerative disease that
affects 7% of the worldwide population, more than 500 million people all over the world. OA …

The ultimate goal of molecular genetic studies of human diseases is to translate the
discoveries for patient benefit. For diseases that lack licensed disease-modifying …