Immunotherapy in the treatment of metastatic melanoma: current knowledge and future directions

M Ralli, A Botticelli, IC Visconti… - Journal of …, 2020 - Wiley Online Library
Melanoma is one of the most immunologic malignancies based on its higher prevalence in
immune‐compromised patients, the evidence of brisk lymphocytic infiltrates in both primary …

Melanoma management: from epidemiology to treatment and latest advances

J Lopes, CMP Rodrigues, MM Gaspar, CP Reis - Cancers, 2022 - mdpi.com
Simple Summary Melanoma is a major public health issue that claims the lives of thousands
of people every year. Furthermore, the outlook for the coming years is not encouraging with …

Melanoma skin cancer detection using deep learning and classical machine learning techniques: A hybrid approach

J Daghrir, L Tlig, M Bouchouicha… - 2020 5th international …, 2020 - ieeexplore.ieee.org
Melanoma is considered as one of the fatal cancer in the world, this form of skin cancer may
spread to other parts of the body in case that it has not been diagnosed in an early stage …

Research progress of microneedles in the treatment of melanoma

X Li, Z Zhao, M Zhang, G Ling, P Zhang - Journal of controlled release, 2022 - Elsevier
Melanoma is an aggressive malignancy deriving from melanocytes, which is characterized
by high tendency of metastases and mortality rate. Current therapies for melanoma, like …

Advanced nanomedicine approaches applied for treatment of skin carcinoma

H Kaur, P Kesharwani - Journal of Controlled Release, 2021 - Elsevier
Skin-cancer is the commonest malignancy affecting huge proportion of the population,
reaching heights in terms of morbidity. The treatment strategies are presently focusing on …

Epidemiology of melanoma

NL Bolick, AC Geller - Hematology/Oncology Clinics, 2021 - hemonc.theclinics.com
Melanoma is the most commonly fatal type of skin cancer and it is an important and growing
public health problem in the United States, Australia, New Zealand, and Europe. Although …

Metformin inhibits melanoma cell metastasis by suppressing the miR-5100/SPINK5/STAT3 axis

D Suwei, X Yanbin, W Jianqiang, M Xiang… - Cellular & Molecular …, 2022 - Springer
Melanoma is the most lethal skin cancer characterized by its high metastatic potential. It is
urgent to find novel therapy strategies to overcome this feature. Metformin has been …

Mechanisms of UV-induced mutations and skin cancer

GP Pfeifer - Genome instability & disease, 2020 - Springer
Ultraviolet (UV) irradiation causes various types of DNA damage, which leads to specific
mutations and the emergence of skin cancer in humans, often decades after initial exposure …

[HTML][HTML] Flexible polymeric patch based nanotherapeutics against non-cancer therapy

H Zhu, JMJ Qiang, CG Wang, CY Chan, Q Zhu, E Ye… - Bioactive Materials, 2022 - Elsevier
Flexible polymeric patches find widespread applications in biomedicine because of their
biological and tunable features including excellent patient compliance, superior …

Frequency of mutations in BRAF, NRAS, and KIT in different populations and histological subtypes of melanoma: a systemic review

LD Gutiérrez-Castañeda, JA Nova… - Melanoma …, 2020 - journals.lww.com
The presence of mutations of BRAF, NRAS, and KIT genes is recognized as playing a role
during carcinogenesis. Our study aims to evaluate and review other studies that present the …