Neurological disorders such as Alzheimer's disease, stroke, and brain cancers are difficult to
treat with current drugs as their delivery efficacy to the brain is severely hampered by the …

Nanomaterials offer unique physical, chemical and biological properties of interest for
medical imaging and therapy. Over the last two decades, there has been an increasing effort …

Brain delivery is one of the major challenges in drug development because of the high
number of patients suffering from neural diseases and the low efficiency of the treatments …

Effective therapy lies in achieving a therapeutic amount of drug to the proper site in the body
and then maintaining the desired drug concentration for a sufficient time interval to be …

In this study, a dual-targeting drug delivery system based on PEGylated oxidized multi-
walled carbon nanotubes (O-MWNTs) modified with angiopep-2 (O-MWNTs-PEG-ANG) was …

Dual-targeting nanoparticle drug delivery system was developed by conjugating Angiopep
with PEG–PCL nanoparticles (ANG-NP) through bifunctional PEG to overcome the …

Nanotechnology has opened up a world of possibilities for the treatment of brain disorders.
Nanosystems can be designed to encapsulate, carry, and deliver a variety of therapeutic …

In many different studies nanocarriers modified with targeting ligands have been used to
target to the brain. Many ligands have been successful, but it is difficult to compare results …

Recent advances in nanotechnology sciences lead to the development of new treatment
approaches for various diseases such as cancer. Nanotechnology advances can potentially …

Therapeutic antibodies have essentially been banned from the central nervous system, and
are so far limited to use mainly in multiple sclerosis. This is primarily due to the fact that …