Arthropod-borne viruses (arboviruses) are taxonomically diverse causes of significant
morbidity and mortality. In recent decades, important mosquito-borne viruses such as West …

In the battle between a virus and its host, innate immunity serves as the first line of defense
protecting the host against pathogens. The antiviral actions start with the recognition of …

The Aedes aegypti mosquito is a vector of many infectious agents, including flaviviruses
such as Zika virus. Components of mosquito saliva have pleomorphic effects on the …

Pathogens have co-evolved with mosquitoes to optimize transmission to hosts. Mosquito
salivary-gland extract is known to modulate host immune responses and facilitate pathogen …

Arboviruses such as dengue (DENV), Zika (ZIKV) and chikungunya (CHIKV) viruses infect
close to half a billion people per year, and are primarily transmitted through Aedes aegypti …

Mosquito saliva facilitates blood meal acquisition through pharmacologically active
compounds that prevent host hemostasis and immune responses. Here, we generated two …

Due to changes in climate, numerous mosquito species are continuously extending their
geographical distributions, posing potential new public health threats as arbovirus infections …

Infection with Zika virus (ZIKV) is of growing concern since infection is associated with the
development of congenital neurological disease. Quantitative reverse transcription PCR …

The skin is an active immune organ that functions as the first and largest site of defense to
the outside environment. Serving as the primary interface between host and pathogen, the …

A recent epidemic of Zika virus in the Americas, affecting well over a million people, caused
substantial mortality and morbidity, including Guillain–Barre syndrome, microcephaly and …