abstract Eosinophils not only play a critical role in the pathogenesis of eosinophil-associated
diseases, but they also have multiple important biological functions, including the …

Eosinophils are complex granulocytes with the capacity to react upon diverse stimuli due to
their numerous and variable surface receptors, which allows them to respond in very …

How helminths influence the pathogenesis of sexually transmitted viral infections is not
comprehensively understood. Here, we show that an acute helminth infection …

As obligate intracellular bacterial pathogens, members of the Chlamydia genera are the
pivotal triggers for a wide range of infections, which can lead to blinding trachoma, pelvic …

Introduction Chlamydia trachomatis (C. trachomatis) is a Gram-negative obligate
intracellular bacterium that causes reproductive tract complications in women, including …

Protective immune responses to Chlamydia infection within the female reproductive tract
(FRT) are incompletely understood. MHC class II-restricted CD4 Th1 responses are believed …

Surveillance and defense of the enormous mucosal interface with the nonsterile world are
critical to protecting the host from a wide range of pathogens. Chlamydia trachomatis is an …

Background Transforming growth factor β1 (TGFβ1) is a cytokine that exerts
immunosuppressive functions, as reflected by its ability to induce regulatory T (Treg) cell …

Chlamydia trachomatis, is a kind of obligate intracellular pathogen. The removal of C.
trachomatis relies primarily on specific cellular immunity. It is currently considered that CD4+ …

Chlamydial infection causes a number of clinically relevant diseases and induces significant
morbidity in humans. Immune and inflammatory responses contribute to both the clearance …