Single-worm long-read sequencing reveals genome diversity in free-living nematodes

YC Lee, HM Ke, YC Liu, HH Lee, MC Wang… - Nucleic Acids …, 2023 - academic.oup.com
Obtaining sufficient genetic material from a limited biological source is currently the primary
operational bottleneck in studies investigating biodiversity and genome evolution. In this …

Model worms: knowledge gains and risks associated with the use of model species in parasitological research

R Poulin - Parasitology, 2023 - cambridge.org
Model parasite species, whose entire life cycle can be completed in the laboratory and
maintained for multiple generations, have played a fundamental role in our understanding of …

A catalogue of chromosome counts for Phylum Nematoda

ML Blaxter, C Leech, DH Lunt - Wellcome Open …, 2024 - wellcomeopenresearch.org
Nematodes are important biological models in genetics and genomics, with research driven
by basic biological as well as applied questions. The presence of holocentric chromosomes …

[HTML][HTML] Chromosome-contiguous genome for the Haecon-5 strain of Haemonchus contortus reveals marked genetic variability and enables the discovery of essential …

Y Zheng, ND Young, TL Campos, PK Korhonen… - International Journal for …, 2024 - Elsevier
Millions of livestock animals worldwide are infected with the haematophagous barber's pole
worm, Haemonchus contortus, the aetiological agent of haemonchosis. Despite the major …

Patterns of Genomic Diversity in a Fig-Associated Close Relative of Caenorhabditis elegans

GC Woodruff, JH Willis… - Genome Biology and …, 2024 - academic.oup.com
The evolution of reproductive mode is expected to have profound impacts on the genetic
composition of populations. At the same time, ecological interactions can generate close …

Multiple Displacement Amplification Facilitates SMRT Sequencing of Microscopic Animals and the Genome of the Gastrotrich Lepidodermella squamata (Dujardin …

NG Roberts, MJ Gilmore, TH Struck, K Kocot - bioRxiv, 2024 - biorxiv.org
Background: Obtaining adequate DNA for long-read genome sequencing remains a
roadblock to producing contiguous genomes from small-bodied organisms. Multiple …

Identification of potential molecular mimicry in pathogen-host interactions

KD Rich, S Srivastava, VR Muthye, JD Wasmuth - PeerJ, 2023 - peerj.com
Pathogens have evolved sophisticated strategies to manipulate host signaling pathways,
including the phenomenon of molecular mimicry, where pathogen-derived biomolecules …

Genome assembly variation and its implications for gene discovery in nematode species

GM Mariene, JD Wasmuth - bioRxiv, 2024 - biorxiv.org
Background: Reduced sequencing costs is facilitating comprehensive BioGenome projects
and sequencing of specific species by individual research groups. While the choice between …

SID-2 localises to extracellular vesicles in parasitic nematodes and does not function in environmental RNAi

F Blow, K Jeffrey, F Wang-Ngai Chow, IA Nikonorova… - bioRxiv, 2024 - biorxiv.org
In the free-living nematode Caenorhabditis elegans the transmembrane protein SID-2
imports double-stranded RNA into intestinal cells to trigger systemic RNA interference …

[PDF][PDF] Biological insights into the parasitic nematode Heligmosomoides bakeri from bulk and single-cell transcriptomics

SMJ Pollo - 2023 - prism.ucalgary.ca
Heligmosomoides bakeri, a parasitic nematode (roundworm) of mice, is closely related to
economically important parasites of livestock and the hookworm parasites of humans. As a …