Functional heterogeneity within rat orbitofrontal cortex in reward learning and decision making

A Izquierdo - Journal of Neuroscience, 2017 - Soc Neuroscience
Rat orbitofrontal cortex (OFC) is located in the dorsal bank of the rhinal sulcus, and is
divided into the medial orbital area, ventral orbital area, ventrolateral orbital area, lateral …

[HTML][HTML] The meaning of behavior: discriminating reflex and volition in the brain

BW Balleine - Neuron, 2019 - cell.com
The ability to establish behaviorally what psychological capacity an animal is deploying—to
discern accurately what an animal is doing—is key to functional analyses of the brain. Our …

Active dendritic currents gate descending cortical outputs in perception

N Takahashi, C Ebner, J Sigl-Glöckner, S Moberg… - Nature …, 2020 - nature.com
The output of cortical columns is routed to different downstream targets via distinct pathways:
cortico-cortical and cortico-subcortical. It is as yet unclear what roles these pathways play in …

Local modulation by presynaptic receptors controls neuronal communication and behaviour

DM Lovinger, Y Mateo, KA Johnson, SA Engi… - Nature Reviews …, 2022 - nature.com
Central nervous system neurons communicate via fast synaptic transmission mediated by
ligand-gated ion channel (LGIC) receptors and slower neuromodulation mediated by G …

The effects of early life stress on reward processing

AM Novick, ML Levandowski, LE Laumann… - Journal of psychiatric …, 2018 - Elsevier
Early life stress (ELS), in the form of childhood maltreatment, abuse, or neglect, increases
the risk for psychiatric sequelae later in life. The neurobiology of response to early stress …

Amygdala-cortical collaboration in reward learning and decision making

KM Wassum - Elife, 2022 - elifesciences.org
Adaptive reward-related decision making requires accurate prospective consideration of the
specific outcome of each option and its current desirability. These mental simulations are …

Multiple memory subsystems: reconsidering memory in the mind and brain

BE Sherman, NB Turk-Browne… - Perspectives on …, 2024 - journals.sagepub.com
The multiple-memory-systems framework—that distinct types of memory are supported by
distinct brain systems—has guided learning and memory research for decades. However …

Specializations for reward-guided decision-making in the primate ventral prefrontal cortex

EA Murray, PH Rudebeck - Nature Reviews Neuroscience, 2018 - nature.com
The estimated values of choices, and therefore decision-making based on those values, are
influenced by both the chance that the chosen items or goods can be obtained (availability) …

CNO evil? Considerations for the use of DREADDs in behavioral neuroscience

SV Mahler, G Aston-Jones - Neuropsychopharmacology, 2018 - nature.com
Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are an
increasingly popular approach for “remotely controlling” selected neuronal populations and …

Distinct cortical–amygdala projections drive reward value encoding and retrieval

M Malvaez, C Shieh, MD Murphy, VY Greenfield… - Nature …, 2019 - nature.com
The value of an anticipated rewarding event is a crucial component of the decision to
engage in its pursuit. But little is known of the networks responsible for encoding and …