Background Tuberculosis (TB) remains a significant cause of mortality globally, yet first-line
treatment has hardly changed for fifty years. The dose of rifampicin, the most important drug …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains one of the world's
deadliest infectious diseases and urgently requires new antibiotics to treat drug-resistant …

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is a tenacious
pathogen that has latently infected one third of the world's population. However …

Diagnosing Buruli ulcer (BU) is complicated by limited access to the sensitive IS 2404
qPCR. Experienced clinicians report a distinct odour of Buruli ulcers. We explored the …

The “successful” Russian clone B0/W148 of Mycobacterium tuberculosis Beijing is well-
known for its capacity to develop antibiotic resistance. During treatment, resistant mutants …

Eradication of tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), has been a
challenge due to its uncanny ability to survive in a dormant state inside host granulomas for …

Currently, the most effective tuberculosis control method involves case finding and 6 months
of chemotherapy. There is a need to improve our understanding about drug interactions …

Epidemiological information and animal models have shown various Mycobacterium
tuberculosis phenotypes ranging from hyper-to hypovirulent forms. Recent genomic and …

Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium
tuberculosis. According to the WHO, the disease is one of the top 10 causes of death of …

DevR/DosR response regulator is believed to participate in virulence, dormancy adaptation
and antibiotic tolerance mechanisms of Mycobacterium tuberculosis by regulating the …