Integrating machine learning and multiscale modeling—perspectives, challenges, and opportunities in the biological, biomedical, and behavioral sciences

M Alber, A Buganza Tepole, WR Cannon, S De… - NPJ digital …, 2019 - nature.com
Fueled by breakthrough technology developments, the biological, biomedical, and
behavioral sciences are now collecting more data than ever before. There is a critical need …

Multiscale modeling meets machine learning: What can we learn?

GCY Peng, M Alber, A Buganza Tepole… - … Methods in Engineering, 2021 - Springer
Abstract Machine learning is increasingly recognized as a promising technology in the
biological, biomedical, and behavioral sciences. There can be no argument that this …

Data-driven modeling of the mechanical behavior of anisotropic soft biological tissue

V Tac, VD Sree, MK Rausch, AB Tepole - Engineering with Computers, 2022 - Springer
Closed-form constitutive models are currently the standard approach for describing soft
tissues' mechanical behavior. However, there are inherent pitfalls to this approach. For …

Propagation of uncertainty in the mechanical and biological response of growing tissues using multi-fidelity Gaussian process regression

T Lee, I Bilionis, AB Tepole - Computer methods in applied mechanics and …, 2020 - Elsevier
A key feature of living tissues is their capacity to remodel and grow in response to
environmental cues. Within continuum mechanics, this process can be captured with the …

Stochastic modeling and identification of a hyperelastic constitutive model for laminated composites

B Staber, J Guilleminot, C Soize, J Michopoulos… - Computer Methods in …, 2019 - Elsevier
In this paper, we investigate the construction and identification of a new random field model
for representing the constitutive behavior of laminated composites. Here, the material is …

Uncertainty quantification of parenchymal tracer distribution using random diffusion and convective velocity fields

M Croci, V Vinje, ME Rognes - Fluids and Barriers of the CNS, 2019 - Springer
Background Influx and clearance of substances in the brain parenchyma occur by a
combination of diffusion and convection, but the relative importance of these mechanisms is …

Biotribology of the ageing skin—Why we should care

G Limbert, MA Masen, D Pond, HK Graham… - Biotribology, 2019 - Elsevier
Ageing of populations has emerged as one of the most pressing societal, economic and
healthcare challenges currently facing most nations across the globe. The ageing process …

Instabilities in liquid crystal elastomers

LA Mihai, A Goriely - MRS Bulletin, 2021 - Springer
Stability is an important and fruitful avenue of research for liquid crystal elastomers. At
constant temperature, upon stretching, the homogeneous state of a nematic body becomes …

Spatially-dependent material uncertainties in anisotropic nonlinear elasticity: Stochastic modeling, identification, and propagation

P Chen, J Guilleminot - Computer Methods in Applied Mechanics and …, 2022 - Elsevier
This paper develops a stochastic model for the spatially-dependent material parameters
parameterizing anisotropic strain energy density functions. The construction is cast within …

[图书][B] Stochastic elasticity: a nondeterministic approach to the nonlinear field theory

LA Mihai - 2022 - books.google.com
Stochastic elasticity is a fast developing field that combines nonlinear elasticity and
stochastic theories in order to significantly improve model predictions by accounting for …