Transient receptor potential (TRP) channels are multifunctional signalling molecules with
many roles in sensory perception and cellular physiology. Therefore, it is not surprising that …

Transient receptor potential canonical (TRPC) channels constitute a group of receptor-
operated calcium-permeable nonselective cation channels of the TRP superfamily. The …

According to the International Association for the Study of Pain (IASP) pain is characterized
as an “unpleasant sensory and emotional experience associated with actual or potential …

Highlights•Neuropathic pain is a chronic condition that represents a major health
problem.•There is a need for new medications with greater efficacy and less adverse …

Simple Summary In this review, recent discoveries regarding transient receptor potential are
discussed and analyzed to comprehend their role in the thermoregulatory mechanisms of …

The concentration of free cytosolic Ca 2+ and the voltage across the plasma membrane are
major determinants of cell function. Ca 2+-permeable non-selective cationic channels are …

The transient receptor potential canonical (TRPC) channels are a group of highly
homologous nonselective cation channels from the larger TRP channel family. They have …

Proteins of the TRPC family can form many homo-and heterotetrameric cation channels
permeable to Na+, K+ and Ca2+. In this review, we focus on channels formed by the …

Abstract Transient Receptor Potential Canonical (TRPC) channels have received more
attention in recent years for their role of in the pathophysiology of chronic pain. These non …

Transient receptor potential canonical (TRPC) channels are highly homologous,
nonselective cation channels that form many homo-and heterotetrameric channels. These …