Biomarkers in hepatocellular carcinoma: diagnosis, prognosis and treatment response assessment

F Piñero, M Dirchwolf, MG Pessôa - Cells, 2020 - mdpi.com
Hepatocellular carcinoma (HCC) is one of the main cancer-related causes of death
worldwide. Thus, there is a constant search for improvement in screening, diagnosis, and …

Hepatic benefits of HCV cure

V Calvaruso, A Craxì - Journal of hepatology, 2020 - Elsevier
Summary Direct-acting antiviral (DAA)-induced HCV clearance conceivably leads to
improved outcomes at all stages of liver disease. However, available data suggest that the …

[HTML][HTML] 2022 KLCA-NCC Korea practice guidelines for the management of hepatocellular carcinoma

Korean Liver Cancer Association - Korean Journal of Radiology, 2022 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the fourth
most common cancer among men in South Korea, where the prevalence of chronic hepatitis …

[HTML][HTML] Antiviral therapy in the palliative setting of HCC (BCLC-B and-C)

M Reig, G Cabibbo - Journal of hepatology, 2021 - Elsevier
The potential impact of direct-acting antivirals (DAAs) in patients with Barcelona Clinic Liver
Cancer (BCLC)-B/C hepatocellular carcinoma (HCC) is understudied. HCC patients have …

Transition to decompensation and acute-on-chronic liver failure: Role of predisposing factors and precipitating events

T Gustot, V Stadlbauer, W Laleman, C Alessandria… - Journal of …, 2021 - Elsevier
The transition from compensated to decompensated cirrhosis results from a complex
interplay of predisposing and precipitating factors and represents an inflection point in the …

[HTML][HTML] The search for disease-modifying agents in decompensated cirrhosis: from drug repurposing to drug discovery

P Caraceni, JG Abraldes, P Ginès, PN Newsome… - Journal of …, 2021 - Elsevier
Patients with decompensated cirrhosis are currently managed through targeted strategies
aimed at preventing or treating specific complications. In contrast, a disease-modifying agent …

Liver cancer risk after HCV cure in patients with advanced liver disease without non-characterized nodules

M Sanduzzi-Zamparelli, Z Mariño, S Lens, V Sapena… - Journal of …, 2022 - Elsevier
Background & Aims Recognition of non-characterized liver nodules (NCLN) prior to direct-
acting antivirals (DAAs) is associated with increased hepatocellular carcinoma (HCC) risk in …

Change in fibrosis 4 index as predictor of high risk of incident hepatocellular carcinoma after eradication of hepatitis C virus

N Tamaki, M Kurosaki, Y Yasui, N Mori… - Clinical Infectious …, 2021 - academic.oup.com
Background It is unclear whether the fibrosis 4 index (FIB-4), a marker of liver fibrosis, at
baseline and change in FIB-4 after sustained virological response (SVR) is associated with …

MAFLD considerations as a part of the global hepatitis C elimination effort: an international perspective

Y Fouad, JV Lazarus, F Negro… - Alimentary …, 2021 - Wiley Online Library
Summary Background The World Health Organization (WHO) set a goal to eliminate
hepatitis C (HCV) infection globally by 2030, with specific targets to reduce new viral …

Outcomes and follow-up after hepatitis C eradication with direct-acting antivirals

EN Lynch, FP Russo - Journal of Clinical Medicine, 2023 - mdpi.com
Treatment of hepatitis C (HCV) has been revolutionized with the introduction of direct-acting
antivirals (DAAs). Patients can be treated at more advanced stages of liver disease, with a …